Results 101 to 110 of about 7,036,024 (258)

Milk production, fluid balance and temperature regulation in lactating camels (Camelus dromedarius) [PDF]

open access: yes, 2010
The aims of this thesis were to identify good milking and watering routines for camels, and to better understand the physiological mechanisms that enable camels to produce milk during long periods of water deprivation.
Bekele, Tafesse
core   +1 more source

Antioxidants, reactive oxygen species and oxidative damage associated to the presence of organochlorine pesticides in breast milk

open access: yesNutrición Hospitalaria
Introduction: Organochlorine pesticides (OCPs) can increase the production of reactive oxygen species (ROS), the effects of which can be countered by the antioxidant system, also present in breast milk.
Patricia Carolina Castillo-Castañeda   +4 more
doaj   +1 more source

Fzd7 Restrains Pink1‐Dependent Mitophagy in Suture Stem Cells to Maintain Cranial Suture Patency

open access: yesAdvanced Science, EarlyView.
How suture stem cells fail to preserve cranial suture patency remains incompletely understood. Integrated single‐cell and high‐resolution spatial transcriptomic analyses identify reduced Fzd7 expression in Prrx1+ suture stem cells as an early feature of craniosynostosis.
Xinyan Chen   +10 more
wiley   +1 more source

Nicotinamide Metabolism Constrains Memory CD8+ T Cell Formation Through a Putative HS1BP3‐SIRT1‐FOXO3‐BCL6 Axis

open access: yesAdvanced Science, EarlyView.
ABSTRACT Memory T cells exhibit long‐term persistence, a defining feature that underpins durable clinical responses to adoptive immunotherapies. The mechanisms that integrate metabolic cues with transcriptional control of memory fate remain undetermined. Here, we identify HS1‐binding protein 3 (HS1BP3) is preferentially expressed in memory CD8+ T cells.
Siyang Wang   +13 more
wiley   +1 more source

Loss of CYLD on Chromosome 16q Impairs Homologous Recombination and Genomic Stability Through TIRR Degradation

open access: yesAdvanced Science, EarlyView.
Chromosome 16q loss drives genomic instability through disruption of the CYLD–TIRR–53BP1 axis. CYLD preserves homologous recombination by stabilizing TIRR and limiting 53BP1 accumulation at DNA double‐strand breaks. CYLD deficiency redirects repair toward error‐prone non‐homologous end joining, promotes mutational burden and homologous recombination ...
Mingming Lu   +14 more
wiley   +1 more source

THE EFFECT OF STRESS ON SMOOTHNESS OF BREAST MILK PRODUCTION IN POSTPARTUM MOTHER IN DELIMA (PARTURITION) ROOM OF SAYANG REGIONAL GENERAL HOSPITAL CIANJUR

open access: yesJurnal Kesehatan Budi Luhur
According to WHO data, the global average rate of exclusive breastfeeding in 2016 was approximately 38%. Many mothers face challenges during breastfeeding, with one common issue being disrupted milk flow.
Dedeh Sri Rahayu   +2 more
doaj   +1 more source

Targeting β2‐Adrenergic Receptor Stability With Lycorine Reveals a Host‐Directed Pathway for Antiviral Defense Against Poxviruses

open access: yesAdvanced Science, EarlyView.
Chronic stress drives autophagy‐mediated β2‐AR degradation, impairing antiviral immunity and promoting poxvirus lethality. Lycorine directly stabilizes β2‐AR to restore host defense, suppress excessive inflammation and improve survival. ABSTRACT Psychological stress is a pervasive yet poorly understood modulator of infectious disease outcomes. Here, we
Xin Zhang   +12 more
wiley   +1 more source

IMPACT OF MILK COOPERATIVES ON MARKETED SURPLUS OF MILK [PDF]

open access: yes
The study conducted during 1994-95 in Jalgaon and Kolhapur districts of Maharashtra showed two differing scenarios insofar as the impact of milk cooperatives on production and marketed surplus is concerned.
Shah, Deepak
core  

ZBTB18 Dysfunction Promotes Neuropathic Pain via CHD4‐based Epigenetic Disinhibition of CLIC1 Channels in Sensory Neurons

open access: yesAdvanced Science, EarlyView.
In this study, we identify a novel functional role of ZBTB18 in regulating trigeminal‐mediated neuropathic pain. Nerve injury reduces ZBTB18 in trigeminal ganglion neurons, impairing CHD4/NuRD recruitment and de‐repressing Clic1. Elevated CLIC1 enhances chloride channel activity and neuronal hyperexcitability, thereby driving pain.
Shoupeng Wang   +11 more
wiley   +1 more source

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