Results 241 to 250 of about 25,541 (288)

Pedunculoside Inhibits Hepatocellular Carcinoma Progression by Activating the MAPK Signaling Pathway Through Targeting and Suppressing CDK4

Phytotherapy Research, EarlyView.
Pedunculoside targets and suppresses CDK4; consequently, it activates the MAPK pathway and inhibits hepatocellular carcinoma progression. ABSTRACT Hepatocellular carcinoma (HCC) remains a major challenge in cancer prevention and treatment, highlighting the urgent need for effective and low‐toxicity anti‐HCC therapies. Recently, CDK4‐targeted inhibitors
Yang Zhou, Jingyun Chi, Yuan Ding, Zhidi Zhang, Rui Liang, Tianhao Wang, Yan Jiang, Rujun Song, Huazhou Fu, Xizhen Zhou   +9 more
wiley   +1 more source

The First 1000 Days of PKU: A Narrative Review of Maternal PKU and Early Life Management After Positive Newborn Screening. [PDF]

Nutrients
Verduci E, Tosi M, Zuvadelli J, Giorda S, Biasucci G, Leuzzi V, Spada M, Burlina A, Dionisi Vici C, PKU Expert Group.   +9 more
europepmc   +1 more source

[Breast feeding and breast milk substitutes. A recent view].

Gaceta medica de Mexico, 1996
L, Vega-Franco, S, Flores-Huerta, J D, Gamboa-Marrufo   +2 more
openaire   +1 more source

Farnesoid X receptor prevents hyperuricemia via activating ATP‐binding cassette subfamily G member 2

Rheumatology &Autoimmunity, EarlyView.
Farnesoid X receptor (FXR) activation reduces serum uric acid levels by upregulating the intestinal urate transporter ATP‐binding cassette subfamily G member 2 (ABCG2). These findings uncover a novel metabolic pathway for urate excretion and suggest that FXR agonists (e.g., obeticholic acid), represent a promising therapeutic strategy for the treatment
Rui Li, Guo Tang, Ye Yu, Guang‐Liang Chen, Liangjing Lu, Juan Wang   +5 more
wiley   +1 more source

European Code Against Cancer, 5th edition - diet, excess body weight, physical activity, sedentary behavior, breastfeeding, and cancer. [PDF]

Mol Oncol
Leitzmann MF, Bakogianni I, Anderson AS, Bauld L, Fernandez E, Morris S, Srour B, Vardavas C, Vlad I, Vuik S, Weijenberg M, Figuls MRI, Rigau D, Feliu A, Zeeb H, Schüz J, D'Souza E, Ritchie D, Espina C, Riboli E.   +19 more
europepmc   +1 more source

Robust Bioconjugated Antigens Induce Immune Responses Preventing Malaria Infection and its Transmission

Small, EarlyView.
Engineered malaria antigens enable in vivo bioconjugation to submicron biopolymer particles in E. coli. Two antigens are co‐tethered at high density and defined stoichiometry. The resulting thermostable particles elicit strong, durable antibody and T‐cell responses, conferring robust protection and blocking mosquito transmission.
Nivethika Sivakumaran, Yevel Flores‐Garcia, Chanel M. Naar, Shuxiong Chen, Mili Mehta, Fijs W. B. van Leeuwen, Abhai Tripathi, Rajagopal Murugan, Meta Roestenberg, Fidel Zavala, Bernd H. A. Rehm   +10 more
wiley   +1 more source

Public policies addressing unhealthy diets in the South-East Asia region: identifying and countering the arguments that undermine policy implementation. [PDF]

Health Policy Plan
Wood B, Sievert K, Sharma N, de Silva PA, Sacks G, Gupta R, Mialon M, Shabnam F, Reeve E.   +8 more
europepmc   +1 more source

Deep Brain Stimulation and Pregnancy: A Case Report and Literature Review

Movement Disorders Clinical Practice, EarlyView.
Verónica Cabreira, Maria José Rosas
wiley   +1 more source

Association Between Selected Flavanols and Isoflavones and Precocious Puberty in Girls-A Scoping Review. [PDF]

Nutrients
Michońska I, Serwin A, Dereń K.
europepmc   +1 more source

Wet Nursing and Human Milk Sharing: Reviving Sustainable Systems to Prioritise Breastfeeding. [PDF]

Matern Child Nutr
Coutsoudis A, Reimers P, Cassey J, Doherty T.   +3 more
europepmc   +1 more source