Results 41 to 50 of about 25,541 (288)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

An exploration of pregnant women and mothers’ attitudes, perceptions and experiences of formula feeding and formula marketing, and the factors that influence decision-making about infant feeding in South Africa

BMC Public Health, 2022
Background Despite strong evidence showing the lifelong benefits of breastfeeding for mothers and children, global breastfeeding practices remain poor.
Christiane Horwood, Silondile Luthuli, Catherine Pereira-Kotze, Lyn Haskins, Gillian Kingston, Sithembile Dlamini-Nqeketo, Gilbert Tshitaudzi, Tanya Doherty   +7 more
doaj   +1 more source

The Uncontroversial Controversy in Compelled Commercial Disclosures [PDF]

, 2019
Federal and state administrative agencies increasingly advance public health goals through the use of mandatory disclosures, like warning labels on cigarettes, that are intended to both inform and influence consumer decisions.
Fowler, Lauren
core   +1 more source

Mechanisms by which sialylated milk oligosaccharides impact bone biology in a gnotobiotic mouse model of infant undernutrition [PDF]

, 2019
Undernutrition in children is a pressing global health problem, manifested in part by impaired linear growth (stunting). Current nutritional interventions have been largely ineffective in overcoming stunting, emphasizing the need to obtain better ...
Ahern, Philip P., Ahmed, Tahmeed, Barile, Daniela, Barratt, Michael J., Cheng, Jiye, Cowardin, Carrie A., Gordon, Jeffrey I., Guruge, Janaki L., Head, Richard D., Hibberd, Matthew C., Huq, Sayeeda, Kung, Vanderlene L., Mills, David A., Sundaresan, Vinaik   +13 more
core   +2 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

酶法制备人乳替代脂的研究进展Research progress on enzymatic preparation of human milk fat substitutes

Zhongguo youzhi
人乳替代脂是一类模拟母乳脂组成的结构脂质，为促进人乳替代脂的绿色高效生产，介绍了母乳脂的甘油三酯组成，对人乳替代脂的酶法制备工艺以及实际应用的研究现状进行了分析、总结和探讨，并展望了未来的研究方向。我国母乳脂中1-油酸-2-棕榈酸-3-亚油酸甘油三酯(OPL)含量最高，其次为1,3-二油酸-2-棕榈酸甘油三酯(OPO)。人乳替代脂的酶法制备工艺包括酯-酯交换法、一步酸解法、醇解-酯化两步法、两步酸解法、酯交换-酸解两步法等。提高酶的催化活性与位置选择性、抑制酰基迁移等是未来酶法制备人乳替代脂的研究方向 ...
陈行飞1，2，张羽飞2,3，李雅丽2，郑明明1，2,3，王俊1 CHEN Hangfei1,2, ZHANG Yufei2,3, LI Yali2, ZHENG Mingming1,2,3, WANG Jun1
doaj   +1 more source

Rapid Assay to Evaluate the Total Antioxidant Capacity in Donkey Milk and in more Common Animal Milk for Human Consumption [PDF]

, 2016
The milk antioxidants, by preventing lipid peroxidation, maintain milk quality, but they also exert a beneficial effect on the consumer’s health, in particular that of infants. Donkey Milk (DM), for its nutritional, functional and bioactive components,
BEGHELLI, Daniela, Bistoni, O, Cavallucci, C, DAMIANO, SILVIA, DE COSMO, Attilio Massimo, LUPIDI, Giulio, POLIDORI, Paolo   +6 more
core  

Quality and Safety Aspects of Infant Nutrition [PDF]

, 2012
Quality and safety aspects of infant nutrition are of key importance for child health, but oftentimes they do not get much attention by health care professionals whose interest tends to focus on functional benefits of early nutrition.
Agostoni C, Agostoni C, Agostoni C, Aris B, Berthold Koletzko, Bier DM, Birlouez-Aragon I, Bonerba E, Cahill SM, Chang H, Dabeka R, Davanzo R, Day JB, Dewey KG, Domellof M, El-Tras WF, Erkekoglu P, Fattal-Valevski A, Fattal-Valevski A, Fattal-Valevski A, Fewtrell MS, Fewtrell MS, Flores JP, Friedman M, Gossner CM, Guzel A, Hamrin P, Hernell O, Hilbig A, Hirvonen T, Jongenburger I, Kaleita TA, Khlangwiset P, Kim SA, Koletzko B, Koletzko B, Koletzko B, Kornreich L, Kvist LJ, Lanska DJ, Lönnerdal B, Malloy MH, Margaret Ashwell, Miled RB, Mitkus RJ, Newberry RE, Norberg S, Oluwafemi F, Panfeng S, Pavesi Arisseto A, Raanan Shamir, Raecker T, Rebhan B, Reij MW, Ruiz E, Santillana MI, Schoder D, Shamir R, Silver LB, Simoneau C, Simoneau C, Snijder CA, Snijder CA, Szajewska H, Szajewska H, Turck D, Weistaub G, Welch RW, Whyatt RM, Willoughby A, Yen TH, Zlotkin S   +71 more
core   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Infant formula feeding and associated factors in Debre Berhan City: A community based cross-sectional study

Heliyon
Introduction: Globally, there is rising concern over the growing reliance on breast milk substitutes (BMSs). However, limited studies have been conducted to explore this issue in Ethiopia.
Fitsum Zekarias Mohammed, Alemtsehaye Gashu, Agmasie Damtew Walle, Michael Amera Tizazu, Besufekad Mulugeta Urgie, Solomon Hailemeskel Beshah   +5 more
doaj   +1 more source