Results 121 to 130 of about 483,397 (304)

Validation of Combined Deep Learning Triaging and Computer-Aided Diagnosis in 2901 Breast MRI Examinations From the Second Screening Round of the Dense Tissue and Early Breast Neoplasm Screening Trial. [PDF]

Invest Radiol, 2023
Verburg E, van Gils CH, van der Velden BHM, Bakker MF, Pijnappel RM, Veldhuis WB, Gilhuijs KGA.   +6 more
europepmc   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Hidden breast neoplasm

, 1990
Se presenta un trabajo realizado a propósito de cuatropacientes portadoras de neoplasma oculto de mamadetectado a partir del hallazgo de metástasis axilares,exclusivamente.Se analiza también el hecho que la adenopatfa axilar,habitualmente del nivel I, puede ser la primeramanifestación clfnica de la enfermedad.Se destaca la importancia de los ...
López Chapuis, Daniel, Laviña, Raúl, Delgado, Fernando, Albo, Manuel   +3 more
openaire   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Features of Breast Cancer Progression after Comprehensive Treatment, Prognosis of Metastatic Spread

Львівський клінічний вісник
Introduction. The effectiveness of breast cancer treatment is directly related to the absence of metastatic spread after comprehensive treatment. Still, there are no clear criteria and algorithms for predicting the occurrence of this complication ...
Yu. Chuprovska, V. Bodiaka, O. Ivashchuk, Ch. Tsagkaris   +3 more
doaj   +1 more source

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

Molecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor, Julio Celis, Ulrik Ringborg   +2 more
wiley   +1 more source

Mammary Myofibroblastoma: A mimicker of benign and low-grade malignant tumors with multipotent mesenchymal differentiation

Current Problems in Cancer: Case Reports
Mammary myofibroblastoma (MFB) is a rare benign spindle cell neoplasm of the breast that can exhibit both epithelial and mesenchymal elements. The histomorphologic features of MFB mimic other potentially more aggressive neoplasms of the breast that may ...
Anthony S. Larson, Amy Song, Lacey J. Schrader, Mark Wickre, Grzegorz T Gurda   +4 more
doaj   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Breast Neoplasm [PDF]

, 2020
openaire   +2 more sources

Acro metastasis: A rare presentation in a common cancer

Current Problems in Cancer: Case Reports
Background: Case presentation: In this study, we presented an Iranian female with triple-negative breast cancer that developed acro-metastasis to the hand Conclusions: However, bone metastasis is the most common kind of neoplasm extension that we can ...
Ali Ghanei-Shahmirzadi, Nasrin Namdari, Maral Mokhtari, Pooya Iranpour   +3 more
doaj   +1 more source