Results 101 to 110 of about 439,387 (353)
A Case Of Atypical Gastric Carcinoma With Osteoclast Like Giant Cells
McGill Journal of Medicine, 2020 Out of all the different types of neoplasms affecting the stomach, gastric carcinomas with Osteoclast-like Giant Cells (OGC) is one of the most uncommon.
Rahul Pandit, Irina Danilova
doaj +1 more source
Second primary cancer risk - the impact of applying different definitions of multiple primaries: results from a retrospective population-based cancer registry study [PDF]
, 2014 Background: There is evidence that cancer survivors are at increased risk of second primary cancers. Changes in the prevalence of risk factors and diagnostic techniques may have affected more recent risks.<p></p> Methods: We examined the
A Chopra +43 more
core +3 more sources
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
Molecular Oncology, EarlyView.In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
Transcutaneous electrical nerve stimulation for cancer pain in adults. [PDF]
, 2008 Background Cancer-related pain is complex and multi-dimensional but the mainstay of cancer pain management has predominately used a biomedical approach. There is a need for non-pharmacological and innovative approaches.
Bennett, Michael I. +4 more
core +1 more source
Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?
Molecular Oncology, EarlyView.Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley +1 more source
An investigational protocol of intraoperative radiotherapy in the treatment of early-stage breast cancer: partial results from the Hospital Israelita Albert Einstein [PDF]
Einstein (São Paulo), 2007 Objective: To describe and assess the experience of the HospitalAlbert Einstein on the treatment of early-stage breast cancer withintraoperative radiotherapy. Methods: Twenty-two patients withinvasive breast cancer, older than 45 years, with tumors ≤ 2.5
Silvio Eduardo Bromberg +7 more
doaj
Sentinel lymph node biopsy in breast neoplasms
Vojnosanitetski pregled, 2009 Background/Aim. Sentinel node (SN) is the first draining node from the malignant tumor site. In the last decade, sentinel node biopsy (SNB) has been introduced as an alternative to axillary dissection in breast cancer. In patients with negative SNB (sentinel node uninvolved with malignancy) axillary dissection is not recommended.
Milan Visnjic +2 more
openaire +4 more sources
Molecular Oncology, EarlyView.Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen +12 more
wiley +1 more source