Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu+17 more
wiley +1 more source
Metastatic Colonic Adenocarcinoma in Breast: Report of Two Cases and Review of the Literature
Metastatic adenocarcinoma to the breast from an extramammary site is extremely rare. In the literature, the most current estimate is that extramammary metastases account for only 0.43% of all breast malignancies and that, of these extramammary sites ...
Jiten P. Kothadia+6 more
doaj +1 more source
Value of Ascitic Lipids in the Differentiation between Cirrhotic and Malignant Ascites [PDF]
Ascitic fluid concentrations of cholesterol, triglycerides and phospholipids, were compared with ascitic fluid total protein in 40 patients with chronic liver disease, 51patients with various neoplasms and 1 patient with cardiac failure.
Alexander L. Gerbes+22 more
core +1 more source
Neoplasm of uncertain behaviour of the breast—a retrospective study in a breast unit [PDF]
Breast lesions include a heterogeneous group of entities with variable clinical behaviour and morphological presentation, mostly classified as benign or malignant, with predictable behaviour. However, there are lesions with clinical, breast imaging and/or biopsy characteristics that do not clarify their nature. These lesions have an uncertain behaviour
Jorge Simões+6 more
openaire +2 more sources
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane+16 more
wiley +1 more source
A Misdiagnosis of a Breast Tumor: Histology Solves It
A breast lump can be benign or malignant, the late one can be primary or metastatic. When the primary neoplasm is unknown the diagnosis, management and treatment maybe quite difficult.
Nádia Rodrigues Silva+4 more
doaj +1 more source
Isolation and Characterization of a Cellular Protein-Lipid Complex from Ascites Fluid Caused by Various Neoplasms [PDF]
High concentrations of lipids in ascites fluid caused by peritoneal carcinomatosis have been described recently. Since their nature has not yet been clarified, we isolated ascitic lipids from 25 patients with various neoplasms for further ...
Caselmann, Wolfgang H., Jüngst, Dieter
core
Triple peptide vaccination as consolidation treatment in women affected by ovarian and breast cancer: clinical and immunological data of a phase I/II clinical trial [PDF]
Vaccination with priming and expansion of tumour reacting T cells is an important therapeutic option to be used in combination with novel checkpoint inhibitors to increase the specificity of the T cell infiltrate and the efficacy of the treatment. In
Antonilli M+13 more
core +1 more source
Papillary neoplasm of the breast – A review and update
Papillary neoplasms of the breast encompass a broad spectrum of lesions that remain one of the most challenging topics in breast pathology. Although recognizing the papillary architecture is straightforward, classification into in situ and invasive can be problematic due to the overlapping features among these lesions. This review focuses on diagnosing
Yihong Wang, Elizabeth C. Song
openaire +2 more sources
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park+6 more
wiley +1 more source