Identification of novel small molecule inhibitors of ETS transcription factors
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla+9 more
wiley +1 more source
Malignant Phyllodes Tumor in an Adolescent Female: A Rare Case Report and Review of the Literature
Primary breast neoplasms are rare in adolescent females, most of which are benign. Phyllodes tumors constitute a remarkably small subset of breast neoplasms (0.3-0.9%) with malignant phyllodes tumors being even more uncommon.
Gabriel S. Makar+5 more
doaj +1 more source
BlazeNeo: Blazing fast polyp segmentation and neoplasm detection [PDF]
In recent years, computer-aided automatic polyp segmentation and neoplasm detection have been an emerging topic in medical image analysis, providing valuable support to colonoscopy procedures. Attentions have been paid to improving the accuracy of polyp detection and segmentation.
arxiv
Studies on the clinical significance of nonesterified and total cholesterol in urine [PDF]
Gas-liquid chromatographic determinations of nonesterified and total urinary cholesterol were performed in 137 normals, 264 patients with various internal diseases without evidence of neoplasias or diseases of the kidney or urinary tract, 497 patients ...
A. Pickel+35 more
core +2 more sources
Secondary neoplasms of the breast [PDF]
A 90-year archive of surgical and postmortem material was reviewed to establish the incidence, presentation, and pathology of tumors secondary to the breast.A search was performed on all cases contained within the files of the Pathology Department of the Royal London Hospital from 1907 to 1999.Sixty patients were identified with unequivocal, secondary,
Stavros N. Georgiannos+3 more
openaire +3 more sources
Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley +1 more source
Granular Cell Tumor of the Breast: Understanding the Cancer Mimic through a Series of Three Cases
Granular cell tumors of breast are rare neoplasms, majority of which are benign. Their imaging appearances are often indistinguishable from breast cancer.
Swati Sharma, Aanchal Shah, Smita Sharma
doaj +1 more source
Cancer mortality in Portugal [PDF]
Following Population News, Trends and Attitudes #6 it was possible to identify that, despite circulatory system diseases represent the leading causes of death (COD) in Portugal, the share of deaths caused by neoplasms is increasing with time.
Ribeiro, Filipe
core
Autophagy in cancer and protein conformational disorders
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
The role of epidermal growth factor-like module containing mucin-like hormone receptor 2 in human cancers. [PDF]
G-protein coupled receptors (GPCRs) are among the most diverse and ubiquitous proteins in all of biology. The epidermal growth factor-seven span transmembrane (EGF-TM7) subfamily of adhesion GPCRs is a small subset whose members are mainly expressed on ...
Bloch, Orin+8 more
core +2 more sources