Results 91 to 100 of about 245,977 (262)

A Novel Theranostic Strategy for Malignant Pulmonary Nodules by Targeted CECAM6 with 89Zr/131I‐Labeled Tinurilimab

Advanced Science, EarlyView.
This study investigates the integrated diagnostic and therapeutic strategy utilizing 89Zr/131I‐labeled tinurilimab for the management of malignant lung nodules, with a particular focus on lung adenocarcinoma (LUAD). CEACAM6, which is highly expressed in most LUAD patients, activates the Src/FAK signaling pathway, thereby promoting cell proliferation ...
Chongyang Chen, Keying Zhu, Jing Wang, Donghui Pan, Xinyu Wang, Yuping Xu, Junjie Yan, Lizhen Wang, Min Yang   +8 more
wiley   +1 more source

Structural and Biochemical Characterization of a Widespread Enterobacterial Peroxidase Encapsulin

Advanced Science, EarlyView.
Encapsulins are self‐assembling bacterial protein compartments loaded with cargo enzymes. The most abundant encapsulin cargo class are Dye‐decolorizing Peroxidases (DyPs). In this study, we structurally and biochemically characterize a DyP encapsulin found in many enterobacteria.
Natalia C. Ubilla‐Rodriguez, Michael P. Andreas, Tobias W. Giessen   +2 more
wiley   +1 more source

Breast Reconstruction (A method for Augmentation) [PDF]

, 1970
S. S. Sethi
openalex   +1 more source

Single‐Cell Analysis Clarifies Pathological Heterogeneity in Tenosynovial Giant Cell Tumor and Identifies Biomarkers for Predicting Disease Recurrence

Advanced Science, EarlyView.
MP3 tumor cells, a specific subpopulation of tumor cells in D‐TGCT, regulated the differentiation of CD34+ Fbs into MMP3+ Fbs and APOE+ Fbs through COL6A3 − (ITGAV + ITGB8) interaction. APOE+ Fbs activated IL‐1B+CCL20+ Mφs through the CXCL12/CXCR4 axis. IL‐1B+CCL20+ Mφs and MMP3+ Fbs participated in the local invasion of D‐TGCT.
Yubin Xie, Chen Chen, Fei Wu, Yiman Peng, Jing Su, Yang Zhao, Hongjie Huang, Zhong Alan Li, Yin Pei, Wencui Li, Yi He, Tianchen Xue, Chenxi Cao, Sui Peng, Xin Zhang, Weidong Song   +15 more
wiley   +1 more source

Ferrocene derivatives with planar chirality and their enantioseparation by liquid‐phase techniques

ELECTROPHORESIS, Volume 44, Issue 1-2, Page 158-189, January 2023., 2023
Abstract In the last decade, planar chiral ferrocenes have attracted a growing interest in several fields, particularly in asymmetric catalysis, medicinal chemistry, chiroptical spectroscopy and electrochemistry. In this frame, the access to pure or enriched enantiomers of planar chiral ferrocenes has become essential, relying on the availability of ...
Paola Peluso, Victor Mamane
wiley   +1 more source

Eosinophils‐Induced Lumican Secretion by Synovial Fibroblasts Alleviates Cartilage Degradation via the TGF‐β Pathway Mediated by Anxa1 Binding

Advanced Science, EarlyView.
Eosinophils play a crucial role in the progression of temporomandibular joint osteoarthritis (TMJOA). This study demonstrates that eosinophils, induced by OVA/IL‐5, promote Lumican secretion in the synovium, which binds to Annexin A1 in chondrocytes, inhibiting transforming growth factor β2 and Smad2/3 phosphorylation.
Wenqian Chen, Yuwei Zhou, Wenxiu Yuan, Yanjing Ou, Hanyu Lin, Kaixun He, Xueshen Qian, Huachen Chen, Chengchaozi Wang, Jie Lu, Weiping Chen, Dexiong Li, Jiang Chen   +12 more
wiley   +1 more source

Co‐producing an inclusive‐care model for young people transitioning from adolescent eating disorder services to adult care: A qualitative study protocol for Transition for Eating Disorder Youth intervention

European Eating Disorders Review, EarlyView., 2023
Abstract Eating disorders (EDs) present a chronic issue to child paediatric mental health services due to their high mortality and relapse rates. The transition from Child and Adolescent Mental Health Services to Adult Mental Health Services is a particularly high‐risk period for young people with EDs given their high vulnerability to change, which can
Maria Livanou, Anya Heneghan, Elli Bouliou, Grace Hill, Katharine Mills, Sophie Naylor Roll, Zara Smalley, Jun Teh, Janet Treasure   +8 more
wiley   +1 more source

Latissimus dorsi reconstruction of the breast. [PDF]

, 1983
Janet Thomas
openalex   +1 more source

Model‐Guided Rational Construction of Escherichia coli Synthetic Consortia for Enhanced 2‐Methylbutyric Acid Production

Advanced Science, EarlyView.
We developed a citramalate‐derived pathway for 2‐methylbutyric acid production in E. coli mono‐culture and consortia. The optimized consortium, using 2‐keto‐3‐methylvalerate as a node, achieved 1817.03 ± 103.73 mg L−1 2‐methylbutyric acid, a 28‐fold increase from the initial strain, with a yield of 0.091 g/g glucose.
Yu Liu, Boyuan Xue, Shaojie Wang, Haijia Su   +3 more
wiley   +1 more source

Reconstruction of the Breast after Mastectomy [PDF]

, 1981
L E Hughes, Don Welsh
openalex   +1 more source