Results 101 to 110 of about 189,014 (298)

Solid Harmonic Wavelet Bispectrum for Image Analysis

Advanced Science, EarlyView.
The Solid Harmonic Wavelet Bispectrum (SHWB), a rotation‐ and translation‐invariant descriptor that captures higher‐order (phase) correlations in signals, is introduced. Combining wavelet scattering, bispectral analysis, and group theory, SHWB achieves interpretable, data‐efficient representations and demonstrates competitive performance across texture,
Alex Brown, Mathilda Avirett‐Mackenzie, Carolin Villforth, Georgios Exarchakis   +3 more
wiley   +1 more source

Organ‐Specific and Conserved Regulatory Logic Orchestrates Gene Expression in the Embryonic Mesothelium

Advanced Science, EarlyView.
Integrated multi‐omic profiling maps the gene‐regulatory landscape of the coelomic mesothelium across heart, lung, and pancreas. A cardiac‐restricted regulatory program is uncovered in which TBX20 activates heart mesothelial (epicardial) cis‐regulatory elements, while MAF emerges as a conserved regulator of mesothelial identity.
Quang Minh Dang, Nicola Smart, Andia Nicole Redpath, Joaquim Miguel Vieira   +3 more
wiley   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

A systematic review of randomised controlled trials in breast reconstruction

Journal of Plastic Surgery and Hand Surgery
Background: For preference sensitive treatments, such as breast reconstructions, there are barriers to conducting randomised controlled trials (RCTs).
Emma Hansson, Camilla Larsson, Alexandra Uusimäki, Karolina Svensson, Emmelie Widmark Jensen, Anna Paganini   +5 more
doaj   +1 more source

Immediate or delayed breast reconstruction after mastectomy: what do women really want [PDF]

, 2018
Breast reconstruction, especially immediate reconstruction after mastectomy has increased over the last decades, at present being regularly offered in many centres worldwide.
Beer, G., Belouli, K., Meyer, V., Vetter, S., Wyss, P.   +4 more
core  

An Implantable Scaffold Sequentially Releasing STING Agonist and B7‐H3 Antibody for Bone Metastasis Immunotherapy

Advanced Science, EarlyView.
We developed an implantable dual‐drug depot using GelMA for bone metastasis treatment, co‐delivering MSA‐2 and αB7‐H3‐loaded CaCO3 microparticles. Sustained release from GelMA scaffold enables MSA‐2 to activate STING signaling and enhance T‐cell infiltration and activation, while sequentially released αB7‐H3 blocks MSA‐2‐induced B7‐H3 upregulation ...
Qijun Lin, Hong Xiao, Shuai Fan, Kaimin Cai, Yanteng Xu, Xinwen Wang, Guanhong Chen, Chuandong Lang, Xinsheng Peng, Mingqiang Li, Yuhu Dai   +10 more
wiley   +1 more source

An investigation of planar array system artefacts generated within an electrical impedance mammography system developed for breast cancer detection [PDF]

, 2014
An Electrical Impedance Mammography (EIM) planar array imaging system is being developed at the University of Sussex for the detection of breast cancers.
Bilal, Rabia, Chatwin, Chris, Khan, Bilal, Young, Rupert   +3 more
core  

Integrating Spatial Proteogenomics in Cancer Research

Advanced Science, EarlyView.
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang, Yang Wu, Feng Zhang, Parthiban Periasamy, Haiyue You, Denise Goh, Rachel Elizabeth Ann Fincham, Xin Ning, Danping Wu, Lu Liu, Ying Jiang, Zhiwen Qian, Joe Yeong, Yan Zhang   +13 more
wiley   +1 more source

DIEP Flap Breast Reconstruction in Patients with Breast Ptosis: 2-Stage Reconstruction Using 3-Dimensional Surface Imaging and a Printed Mold

Plastic and Reconstructive Surgery, Global Open, 2017
Background:. Autologous breast reconstruction can be performed for breasts with ptosis to a certain extent, but if patients desire to correct ptosis, mastopexy of the contralateral breast is indicated.
Koichi Tomita, MD, PhD, Kenji Yano, MD, PhD, Mifue Taminato, MD, Michiko Nomori, MD, Ko Hosokawa, MD, PhD   +4 more
doaj   +1 more source

Quantifying admissible undersampling for sparsity-exploiting iterative image reconstruction in X-ray CT

, 2012
Iterative image reconstruction (IIR) with sparsity-exploiting methods, such as total variation (TV) minimization, investigated in compressive sensing (CS) claim potentially large reductions in sampling requirements.
Jørgensen, Jakob H., Pan, Xiaochuan, Sidky, Emil Y.   +2 more
core   +1 more source