Results 91 to 100 of about 189,014 (298)

Breast reconstruction.

Experimental oncology, 2014
Mastectomy has been used for the treatment of breast cancer for many years, but the importance of the positive psychosocial benefits of breast reconstruction in breast cancer treatment has been recognized in the past years. Now, more women seek breast reconstruction and surgeons perform more reconstructions. A breast can be reconstructed by two methods:
Kaya, B., Serel, S.
openaire   +2 more sources

Unraveling the Molecular Mechanisms Underlying Spontaneous Multipolar Mitosis Through CIN‐seq

Advanced Science, EarlyView.
Multipolar mitosis, a hallmark of chromosomal instability (CIN), drives tumor heterogeneity but is challenging to study in live cells. Using CIN‐seq, a single‐cell multiomics method, we profiled rare CIN events and identified mechanisms associated with viable multipolar mitosis, including PTEN attenuation, Rho GTPase‐driven cytokinesis failure, and ...
Pin‐Rui Su, Ting‐Chun Chou, Maria Teresa López‐Cascales, Junfeng Huang, Tsai‐Ying Chen, Sjoukje van Wieren, Chan Li, Cecile Beerens, Li You, Jelle Storteboom, Miao‐Ping Chien   +10 more
wiley   +1 more source

Satisfaction with cosmetic outcomes of breast reconstruction: Investigations into the correlation between the patients’ Breast-Q outcome and the judgment of panels

JPRAS Open, 2020
Summary: Objectives: We aimed to determine the relation between breast reconstruction method, patient satisfaction, and surgeon reported cosmetic outcome among women who underwent breast reconstruction after mastectomy.
Y. Eltahir, E. Bosma, N. Teixeira, P.M.N. Werker, G.H. de Bock   +4 more
doaj   +1 more source

Contralateral prophylactic mastectomies. Correlations between primary tumor and histological findings of controlateral breast [PDF]

, 2016
Backgound: In Italy in 2015 48,000 new cases of breast carcinomas were diagnosed. Women who are diagnosed with breast cancer have a significant risk of developing contralateral breast cancer during the rest of their lives and this risk is closely ...
Amanti, Claudio, Argento, Giuseppe, Campanella, L, Cunsolo, G, DI STEFANO, Domenica, Lombardi, Augusto, Maggi, Stefano, Mastrangeli, Mr, Mattei, Ms, Stanzani, G, Vitale, Valeria   +10 more
core   +1 more source

CRP Deficiency Rescues Periodontitis‐Induced Hippocampal Neurogenesis Impairment by Suppressing OPC‐Derived BMP4 Signaling in Rats

Advanced Science, EarlyView.
Chronic periodontitis elevates circulating CRP, which enters the hippocampus to upregulate BMP4 in oligodendrocyte precursor cells (OPCs), thereby impairing neurogenesis and inducing anxiety/depression‐like behaviors in rats. Counteracting this pathway, CRP deficiency helps confer functional resilience to OPCs.
Lingjie Li, Ping Deng, Siyu Hou, Xianbo Xia, Wei Zhao, Xingyu Zhu, Yang Zhang, Chao Wang, Ling Xu, Jinlin Song   +9 more
wiley   +1 more source

Breast Reconstruction after Mastectomy [PDF]

, 2010
Results of our analysis show as that breast reconstruction become a standard part of the care of female patients with breast cancer. We will analyse the factors that are important for the primary or secondary breast reconstruction after mastectomy, and ...
Milomir Ninković, Stipan Janković, Zdravko Roje, Željka Roje   +3 more
core   +1 more source

Oncoplastic conservative surgery for breast cancer: long-term outcomes of our first ten years experience [PDF]

, 2018
The main goal of oncoplastic breast surgery (OBS) is to optimize cosmetic outcomes and reduce patient morbidity, while still providing an oncologically-safe surgical outcome and extending the target population of conservative surgery.
Barellini, L, Calabrese, C, Casella, D, Di Taranto, G, Fausto, A, Kothari, A, Lo Torto, F, Marcasciano, M, Perra, Agostino, Ribuffo, D, Sordi, S, Tarallo, M   +11 more
core   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

Hierarchical Targeting of TREM2+ Myeloid Cells via Acid‐Triggered OMVs Reprogram Immunosuppression and Suppress Osteolysis in Bone‐Metastatic TNBC

Advanced Science, EarlyView.
This study developed a hierarchical targeting nanoplatform, siTREM2@ETP‐PEOz‐OMVs, against triple‐negative breast cancer (TNBC) bone metastasis. It precisely delivers therapeutic siTREM2 to monocytes/macrophages within the metastatic niche. This intervention dually regulates cell fate: reprogramming immunosuppressive macrophages and inhibiting ...
Fanglu Chen, Yucheng Xue, Xiao Ma, Liang Chen, Zhenxuan Shao, Hangxiang Sun, Haochen Mou, Fangqian Wang, Zilong Li, Yechao Shen, Zhaoming Ye, Xiaohua Yu, Shengdong Wang   +12 more
wiley   +1 more source

The Influence of Patient Exposure to Breast Reconstruction Approaches and Education on Patient Choices in Breast Cancer Treatment. [PDF]

, 2019
BackgroundThe landscape of surgical and medical management and patient choices for breast cancer treatment changes as breast reconstruction and oncoplastic approaches improve and diversify.
Blair, Sarah L, Dobke, Marek K, Mackert, Gina A, Yee, Brittany, Zhu, William Y   +4 more
core