Results 131 to 140 of about 193,726 (322)

Dopamine D1 Receptor Contributes to Glucocorticoid‐Associated Osteonecrosis of Femoral Head Protection Through the ATF3/CHOP Axis to Inhibit Osteoblastic Apoptosis

Advanced Science, EarlyView.
This work identifies a novel mechanism by which dopamine D1 receptor (DRD1) contributes to the pathogenesis of glucocorticoid (GC)‐associated osteonecrosis of the femoral head (ONFH) through the regulation of osteoblastic apoptosis, indicating that DRD1 serves as a critical mediator of the crosstalk between the nervous and skeletal systems.
Kai Zheng, Wenming Li, Tianhao Wang, Gaoran Ge, Wei Zhang, Yi Qin, Wenhao Li, Zebin Wu, Zhen Wang, Gang Rui, Yaozeng Xu, Dechun Geng   +11 more
wiley   +1 more source

Single‐Cell RNA Sequencing Identifies MMP11+ Cancer‐Associated Fibroblasts as Drivers of Angiogenesis and Bladder Cancer Progression

Advanced Science, EarlyView.
Single‐cell RNA sequencing identifies MMP11⁺ CAFs as pro‐angiogenic cells accumulating during bladder cancer progression. These cells promote angiogenesis by regulating ESM1⁺ tip endothelial cells and recruiting SPP1⁺ macrophages. Tumor‐derived BMP2 promotes their activation.
Wuwu Xu, Ting Liang, Hu Fang, Lu Fu, Dashi Deng, Xiyang Tan, Lisha Liu, Dongdong Tang, Haoxiang Zheng, Qiuxia Ding, Xiuqi Hou, Daquan Feng, Tao Tao, Song Wu   +13 more
wiley   +1 more source

Giant fibroadenoma of the breast: Immediate reconstruction following excision

, 1978
Saul D. Hoffman
openalex   +1 more source

An Explainable Multimodal Artificial Intelligence Model Integrating Histopathological Microenvironment and EHR Phenotypes for Germline Genetic Testing in Breast Cancer

Advanced Science, EarlyView.
This study presents an explainable multimodal AI model, MAIGGT (Multimodal Artificial Intelligence Germline Genetic Testing), that combines whole‐slide histopathology with clinical data for accurate germline BRCA1/2 mutation prescreening. By integrating digital pathology and EHR phenotypes, MAIGCT enables cost‐effective, scalable hereditary breast ...
Zijian Yang, Changyuan Guo, Jiayi Li, Yalun Li, Lei Zhong, Pengming Pu, Tongxuan Shang, Lin Cong, Yongxin Zhou, Guangdong Qiao, Ziqi Jia, Hengyi Xu, Heng Cao, Yansong Huang, Tianyi Liu, Jian Liang, Jiang Wu, Dongxu Ma, Yuchen Liu, Ruijie Zhou, Xiang Wang, Jianming Ying, Meng Zhou, Jiaqi Liu   +23 more
wiley   +1 more source

Reconstruction of the female breast after bilateral simple mastectomy

, 1970
W.A. Hauschild
openalex   +1 more source

Aesthetic refinements in autogenous breast reconstruction [PDF]

, 1998
J MICHAELDREVER
openalex   +1 more source

HLA‐DR⁺ Tumor Cells Show an Association with a Distinct Immune Microenvironment and CD8⁺ T‐Cell Exhaustion in HBV‐Associated Hepatocellular Carcinoma

Advanced Science, EarlyView.
This study integrates scRNA‐seq, multiplex immunofluorescence, and clinical data to identify HLA‐DR⁺tumor cells uniquely enriched in Hepatocellular carcinoma (HCC) with hepatitis B virus (HBV). These cells express MHC II, associate with PD‐L1, recruit and exhaust CD8⁺T cells, predict poor survival, and serve as potential biomarkers for immunotherapy ...
Jun‐Qing Chang, Yan Guo, Wen‐Jing Yuan, Yu‐Man Chen, Bo‐Wei Liu, Wen‐Tao Li, Xiang‐Ming Ding, Xu‐Dong Fu, Yu‐Han Lou, Zhuo‐Ran Chen, Xiao‐Ying Luo, Song‐Ze Ding, Bing‐Yong Zhang, Xiu‐Ling Li, Yong‐Zhi Hong, Shun‐Dong Cang, Dong‐Xiao Li, Ling Lan   +17 more
wiley   +1 more source

Deciphering Cell Type Abundance in Proteomics Data Through Graph Neural Networks

Advanced Science, EarlyView.
GraphDEC constructs pseudo bulk reference data using a mixup strategy, then learns low dimensional representations via autoencoders to model intra and inter dataset relationships. These are processed through a multi view adaptive neighborhood aware GNN, integrating reference, target, and joint graphs.
Zhiming Dai, Yujie Song, Tuoshi Qi, Hongyu Zhang, Huiying Zhao, Zheng Wang, Yuedong Yang, Yuansong Zeng   +7 more
wiley   +1 more source

Manipulating Liquid‐Liquid Interphase Solute Diffusion for the Construction of Non‐Symmetric Metal‐Quinone Network Nanoarchitectonics and Nano‐Motorization

Advanced Science, EarlyView.
Non‐symmetric metal‐quinone network (MQN) nanoarchitectonics with controllable morphology and size are constructed by manipulating interphase solute diffusion during the nanoprecipitation process. Self‐propelled nanomotors developed from non‐symmetric MQN nanoarchitectonics exhibit chemotactic autonomous motion toward overexpressed H2O2 in tumor ...
Wenzhe Xu, Yingke Xue, Yang Chen, Ruixu Yang, Shuwei Liu, Yi Liu, Hao Zhang   +6 more
wiley   +1 more source

Awareness and Acceptability of Breast Reconstruction Among Women with Breast Cancer in Twin Cities of Islamabad and Rawalpindi

Life and Science
Objective: To determine the frequency of awareness and acceptability of breast reconstruction surgery among women in the twin cities of Islamabad and Rawalpindi. Study Design: Cross-sectional study. Place and Duration of Study: The study was carried out
Mehwish Mehmood, Ayesha Aslam, Waqas Ahmed, Sameena Aman, Ahmed Ali, Hira Feroze, Nousheen Saleem   +6 more
doaj   +1 more source