Results 141 to 150 of about 245,977 (262)

Immunosuppressive JAG2+ tumor‐associated neutrophils hamper PD‐1 blockade response in ovarian cancer by mediating the differentiation of effector regulatory T cells

open access: yesCancer Communications, EarlyView.
Abstract Background Tumor‐associated neutrophils (TANs) play a critical role in modulating immune responses and exhibit significant heterogeneity. Our previous study demonstrated that jagged canonical Notch ligand 2 (JAG2)+ TANs were associated with an immunosuppressive microenvironment in high‐grade serous ovarian cancer (HGSOC), but the underlying ...
Chenyang Wang   +11 more
wiley   +1 more source

Neutrophils in cancer: At the crucial crossroads of anti‐tumor and pro‐tumor

open access: yesCancer Communications, EarlyView.
Abstract Neutrophils are important components of the immune system and play a key role in defending against pathogenic infections and responding to inflammatory cues, including cancer. Their dysregulation indicates potential disease risk factors. However, their functional importance in disease progression has often been underestimated due to their ...
Wenpeng Cai   +6 more
wiley   +1 more source

Expandable anatomical implants in breast reconstructions: a prospective study

open access: bronze, 1998
Shahab Mahdi   +3 more
openalex   +1 more source

Radiation therapy and breast reconstruction: complications and cosmesis with tram versus tissue expanders [PDF]

open access: hybrid, 2001
Akhil Chawla   +5 more
openalex   +1 more source

Positron emission tomography: Evolving modalities, radiopharmaceuticals and professional collaboration

open access: yesJournal of Medical Radiation Sciences, Volume 69, Issue 4, Page 415-418, December 2022., 2022
PET has experienced exponential growth over the last few decades in terms of innovative technologies and novel radiopharmaceuticals. This has fostered increasing collaboration between radiographers and nuclear medicine technologists. Abstract Positron emission tomography (PET) as an imaging modality has undergone considerable innovation over the past ...
Sally L. Ayesa, Andrew Murphy
wiley   +1 more source

Exploring the Stability and Substrate Profile of Transaminase from Silicibacter pomeroyi with Ancestral Sequence Reconstruction

open access: yesChemBioChem, Accepted Article.
Amine transaminases (ATAs), belonging to the class III transaminases within the superfamily of pyridoxal‐5'‐phosphate (PLP)‐dependent enzymes, catalyze transamination reactions between amino donors and amino acceptors. These enzymes are particularly appealing for their role in the stereospecific synthesis of chiral amines.
Luyao Zhao   +4 more
wiley   +1 more source

Variety of Immediate Breast Reconstruction after Mastectomy for Breast Cancer

open access: gold, 1998
B. C. Choi   +4 more
openalex   +1 more source

PLK4: Master Regulator of Centriole Duplication and Its Therapeutic Potential

open access: yesCytoskeleton, EarlyView.
ABSTRACT Centrosomes catalyze the assembly of a microtubule‐based bipolar spindle, essential for the precise chromosome segregation during cell division. At the center of this process lies Polo‐Like Kinase 4 (PLK4), the master regulator that controls the duplication of the centriolar core to ensure the correct balance of two centrosomes per dividing ...
Muhammad Hamzah   +2 more
wiley   +1 more source

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