Results 161 to 170 of about 193,726 (322)

Targeting Hyperglycemic Bone Pre‐Metastatic Niche for Breast Cancer Bone Metastasis Therapy

Advanced Science, EarlyView.
This study reveals that breast cancer creates a hyperglycemic pre‐metastatic niche in bone prior to colonization and amplifies glucose metabolism post‐metastasis. To target this mechanism, a biomimetic enzyme‐engineered nanoplatform that disrupts tumor glycolytic pathways, proposing a therapeutic strategy to inhibit breast cancer bone metastasis by ...
Jianxin Ye, Peng Hu, Rui Zhang, Lei Zhou, Zonghua Luo, Yanan Chen, Shengzhe Ruan, Mengyi Zhu, Huaze Ding, Yike Qian, Yan Xing, Tong Meng, Changping Wang, Dianwen Song   +13 more
wiley   +1 more source

Expandable anatomical implants in breast reconstructions: a prospective study

, 1998
Shahab Mahdi, Terry M. Jones, Sean Nicklin, D.D. McGeorge   +3 more
openalex   +1 more source

Adipose Tissue Macrophages as Initiators of Exacerbated Periodontitis in Estrogen‐Deficient Environments via the Amplifier Extracellular Vesicles

Advanced Science, EarlyView.
Chronic systemic inflammation, worsened by estrogen deficiency, underlies and exacerbates periodontitis. Proinflammatory macrophages within visceral adipose tissue are hyperactivated due to hyper‐DNA methylation, releasing small extracellular vesicles (sEVs) similar to those of their parent cells.
Danfeng Li, Tian Yang, Yuqian Li, Xinwei Lyu, Cheng Hu, Jiayin Yan, Jiali Tan   +6 more
wiley   +1 more source

Nipple‑sparing mastectomies: Clinical outcomes from a single academic institution [PDF]

, 2017
Conant, Leah, Cyr, Amy, Dull, Barbara, Margenthaler, Julie A, Myckatyn, Terence, Tenenbaum, Marissa   +5 more
core   +2 more sources

Thermal injuries in autogenous tissue breast reconstruction

, 1998
Maurice Y. Nahabedian, B M McGibbon
openalex   +1 more source

Radiation therapy and breast reconstruction: complications and cosmesis with tram versus tissue expanders [PDF]

, 2001
Akhil Chawla, Alphonse G. Taghian, Simon N. Powell, Sherif Assaad, Daniel T Zapton, Lisa A. Kachnic   +5 more
openalex   +1 more source

FBXO2 Alleviates Intervertebral Disc Degeneration via Dual Mechanisms: Activating PINK1‐Parkin Mitophagy and Ubiquitinating LCN2 to Suppress Ferroptosis

Advanced Science, EarlyView.
F‐box only protein 2 (FBXO2) combats intervertebral disc degeneration (IVDD) by coordinating dual protection. It activates PTEN‐induced putative kinase 1 (PINK1)‐Parkin mitophagy restoring mitochondrial function and targets lipocalin‐2 (LCN2) for degradation, suppressing ferroptosis.
Tongde Wu, Yanjin Wang, Beiduo Shen, Kai Guo, Ziqi Zhu, Yongzhou Liang, Jianhua Zeng, Desheng Wu   +7 more
wiley   +1 more source

SGCD: High‐Resolution Spatial Domain Characterization via Data Interpolation and Cell‐Type Deconvolution

Advanced Science, EarlyView.
SGCD presents a novel approach for tissue spatial domain identification by employing interpolation to estimate inter‐spot gene expression and deconvolution to resolve cell‐type composition in both sampled and interstitial regions. By integrating gene expression, cell type, and spatial coordinates within a graph contrastive learning framework, SGCD ...
Tianjiao Zhang, Shenghe Li, Ruolan Zhang, Hongfei Zhang, Zhongqian Zhao, Hao Sun, Zhenao Wu, Guohua Wang   +7 more
wiley   +1 more source

"Microsurgical breast reconstruction - A salvage option for failed implant-based breast reconstruction". [PDF]

Breast
Bigdeli AK, Tee JW, Vollbach FH, Diehm YF, Falkner F, Strübing F, Mahrhofer M, Gazyakan E, Kneser U, Siegwart LC.   +9 more
europepmc   +1 more source

Variety of Immediate Breast Reconstruction after Mastectomy for Breast Cancer

, 1998
B. C. Choi, Sang Hyun Woo, Jae Ho Jeong, Jung Hyun Seul, Soo Jung Lee   +4 more
openalex   +1 more source