Results 171 to 180 of about 2,218,448 (337)

Single‐Cell Mitochondrial Lineage Tracing Decodes Fate Decision and Spatial Clonal Architecture in Human Hematopoietic Organoids

Advanced Science, EarlyView.
This study repurposes mitochondrial DNA mutations as endogenous barcodes for lineage tracing in human pluripotent stem cell‐derived organoids. Integrated with transcriptomic and spatial data, it reveals NOTCH‐mediated stromal‐progenitor crosstalk orchestrates clonal dynamics and spatial zonation during early hematopoietic development, offering a non ...
Yan Xue, Junhao Su, Yiming Chao, Lu Liu, Xinyi Lin, Yang Xiang, Mun Kay Ho, Zezhuo Su, Junyi Chen, Zhuojuan Luo, Chengqi Lin, Ruibang Luo, Theo Aurich, Jianfeng Wu, Kelvin Sin Chi Cheung, Yuanhua Huang, Joshua W. K. Ho, Ryohichi Sugimura   +17 more
wiley   +1 more source

The Impact of Closed Incision Negative Pressure Therapy on Postoperative Breast Reconstruction Outcomes

, 2018
Allen Gabriel, Steven Sigalove, Noemi M. Sigalove, Toni Storm‐Dickerson, Jami Rice, Patrick Maxwell, Leah Griffin   +6 more
openalex   +1 more source

Mechanical Stimuli‐Induced Manipulation of Malignant Behavior in Bioprinted Cancer Microtissues via PI3K/NF‐κB Activation

Advanced Science, EarlyView.
A mechanically tunable ECM platform is created by integrating dECM–alginate matrices with in‐bath tumor printing. The mechanically tunable ECM environment drives tumors to acquire hypoxia, mechanotransduction signaling, metastatic traits, and drug‐resistant phenotypes that collectively promote malignant transformation.
Seok‐Hyeon Lee, Jeongho Lee, Min‐Seo Choi, Minjun Ahn, Sik Yoon, Dongjun Lee, Sae‐Ock Oh, Won‐Woo Cho, Byoung Soo Kim   +8 more
wiley   +1 more source

Early Use and Outcomes of Polydioxanone Mesh in Implant-based Breast Reconstruction. [PDF]

Plast Reconstr Surg Glob Open
Sulkar RS, Chung AY, Hilmer MK, Vose JG, Duffy FJ, Seth AK, Becker H.   +6 more
europepmc   +1 more source

Biomechanics‐Driven 3D Architecture Inference from Histology Using CellSqueeze3D

Advanced Science, EarlyView.
CellSqueeze3D reconstructs 3D cellular architecture from standard 2D histology images using biomechanical constraints and optimization. Validated on clinical datasets, it enables accurate tissue phenotyping, predicts gene mutations, and reveals significant correlations between nuclear‐cytoplasmic ratio entropy and tumor progression.
Yan Kong, Hui Lu
wiley   +1 more source

Exploring Breast Reconstruction in Late-stage Breast Cancer Patients. [PDF]

Plast Reconstr Surg Glob Open
Haddock NT, Troia TC, Kim LJ, Teotia SS.
europepmc   +1 more source

CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target

Advanced Science, EarlyView.
This review conceptualizes CD147 as a fundamental “Energy‐Structure Coupler,” physically bridging metabolic flux (via MCTs) with morphogenetic plasticity (via integrins/MMPs) to drive cancer, infection, and autoimmunity. Addressing the “specificity paradox” that limits current translation, the authors chart a strategic roadmap—spanning logic‐gated ...
Xiang‐Min Yang, Huijie Bian, Zhi‐Nan Chen   +2 more
wiley   +1 more source

Redefining Reconstruction: Technological Innovations in Microsurgical Breast Reconstruction. [PDF]

Cancers (Basel)
Speck NE, Farhadi J.
europepmc   +1 more source

D133. One And Done?: Predictors Of Revision And Additional Operations Following Two-stage Tissue Expander To Implant-based Breast Reconstruction

Minji Kim, Uchechukwu O. Amakiri, Lillian A. Boe, Charles Jiang, Carrie S. Stern, Babak J. Mehrara, Jonas A. Nelson   +6 more
openalex   +1 more source

Breast reconstruction after mastectomy for breast cancer [PDF]

, 2011
Jonathan Platt, Nancy N. Baxter, Toni Zhong   +2 more
openalex   +1 more source