FEBS Open Bio, EarlyView.We provide a step‐by‐step guide for producing E140 antigen fragments from Plasmodium berghei (Pb1) and Plasmodium vivax (Pv1). Pb1/Pv1 are expressed in E. coli, solubilized by freeze–thawing, refolded by slow dilution, purified by affinity chromatography (IMAC), then concentrated and subjected to quality control.
Rodolfo Ferreira Marques +5 more
wiley +1 more source
Fat necrosis following breast reduction
, 1994 Apostólos D. Mandrekas +3 more
openalex +1 more source
Induction of breast cancer resistance protein by the camptothecin derivative DX-8951f is associated with minor reduction of antitumour activity [PDF]
, 2002 Annemarie H. van Hattum +9 more
openalex +1 more source
A potential tumor suppressor role of PLK2 in glioblastoma
FEBS Open Bio, EarlyView.PLK2 was consistently downregulated in GBM tissues. Overexpression of PLK2 in GBM cell lines U87MG and U251 reduced their tumorigenic potential and enhanced cell cycle arrest and apoptosis. Suggesting that PLK2 overexpression could potentially be leveraged as a therapeutic strategy to inhibit tumor progression and enhance apoptosis, providing new ...
Xiangping Xia +5 more
wiley +1 more source
Chemoprevention for Primary Breast Cancer Risk Reduction for Women at High Risk of Breast Cancer: Implementing an Evidence-Based Recommendation [PDF]
, 2016 This capstone project was an evidence-based quality improvement project with three objectives: (a) to understand current practice of primary breast cancer chemoprevention in an integrated health system; (b) to evaluate the most current evidence available
Kottman, Linda M.
core +1 more source
Validation study of risk-reduction activities after personalized breast cancer education tool in the WISDOM study. [PDF]
Breast cancer risk reduction strategies have been well-validated, but barriers remain for high-risk individuals to adopt them. We performed a study among participants with high risk of breast cancer to validate whether a virtual breast health decision ...
Belkora, Jeffrey +10 more
core +1 more source
Significant Reduction in Breast Cancer Risk for Japanese Women with Interleukin 1B -31 CT/TT Relative to CC Genotype [PDF]
, 2002 Lucy S. Ito
openalex +1 more source
FEBS Open Bio, EarlyView.This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi +2 more
wiley +1 more source
Outcomes analysis of breast reduction in Brazilian women using the BREAST-Qs questionnaire: a crosssectional controlled study [PDF]
, 2019 OBJECTIVE: The aim of this study was to analyse patient-reported outcomes of reduction mammoplasty among Brazilian women. METHODS: A total of 100 women were enrolled in this cross-sectional controlled study, 50 with breast hypertrophy (Hypertrophy Group)
Aguiar, Isabella de Carvalho +5 more
core +1 more source
“The reason for hating myself”: a patient's request for breast reduction
, 1996 A.R. Green
openalex +1 more source