Results 191 to 200 of about 858,528 (292)

Cell and Gene Therapies Manufacturing Challenges and Integrated Good Manufacturing Practices Solutions: A Lifecycle Perspective

Biotechnology and Bioengineering, EarlyView.
Lifecycle perspective on cell and gene therapy manufacturing challenges and enabling GMP solutions. ABSTRACT Cell and gene therapies (CGTs) are revolutionizing modern medicine; however, making these advanced medicines scalable and readily available to commercial manufacturers worldwide is a major challenge. The number of approved CGT products continues
Rajath Samaga, Udisha Singh, Sachin Dattram Pawar   +2 more
wiley   +1 more source

Thirteen Years of Reconstructive Breast Surgery in a Korean Tertiary Practice: Procedure Spectrum, Shifting Practice, and Modality Selection in 2216 Patients. [PDF]

Medicina (Kaunas)
Kang B, Jang W, Park J, Lee IH, Moon JS, Lee J, Park HY, Ryu JY, Choi KY, Yang JD, Chung HY, Lee JS.   +11 more
europepmc   +1 more source

GlycoMAC: A Multiscale Metabolic‐Glycosylation Framework for Predicting Glycosylation Across Conditions in Mammalian Cell Cultures

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Antibody productivity and glycosylation quality in CHO cell cultures emerge from a dynamically evolving metabolic environment, yet existing models often work in isolation or at a single scale. Here, we present a multiscale mechanistic framework linking molecular, cellular, and macroscopic scales to predict how inputs shape bioprocess ...
Yuming Zeng, Sarah W. Harcum, Jinxiang Pei, Wei Xie   +3 more
wiley   +1 more source

Beyond survival: reconstructing body image and femininity after breast cancer. [PDF]

Rev Assoc Med Bras (1992)
Piato A, Piato JRM, Mota BS, Filassi JR, Baracat EC, Soares Júnior JM.   +5 more
europepmc   +1 more source

Batch‐to‐Batch Optimization of pH Shifts in CHO Bioreactor Operations

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Culture pH is an important operating parameter in CHO cell cultures producing mAb since it directly affects growth and specific productivity. Mathematical models can be used to optimize the magnitude and timing of pH shifts provided that they are robust to model errors.
Ali Ghodba, Zahra Negahban, Anne Richelle, Chris McCready, Valerie Ward, Luis Ricardez‐Sandoval, Hector Budman   +6 more
wiley   +1 more source

Surgical Management of Posttraumatic Breast Bisection Following Seat Belt Injury: A Series of 3 Cases and Technique Description. [PDF]

Aesthet Surg J Open Forum
Bussy A, Frobert P, Vaucher R, Perez S, Dupuy F, Delay E.   +5 more
europepmc   +1 more source

Metal nanostructure‐coupled label‐free localized surface plasmon resonance biosensors for rapid and sensitive disease diagnosis

BMEMat, EarlyView.
LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng, Yunfei Sha, Jiongyan Yang, Hongru Yang, Xiao Liang   +4 more
wiley   +1 more source

Efficacy and Safety of the L-Scar Technique in Breast Surgery: A Systematic Review and Meta-Analysis. [PDF]

Aesthetic Plast Surg
Machado Magalhães PL, Collaco BG, Guerreiro MG, da Silva AMP, Falcão L, Amaral DC, Silva RAS, de Bastos Maximiano ML, de Almeida IA, Silva YP, Pinto BGB, Elegbede AI.   +11 more
europepmc   +1 more source

Nanomedicine‐driven innovations in postoperative cancer immunotherapy: Remodeling tumor microenvironment and precision delivery strategies

BMEMat, EarlyView.
Nanomedicine‐Driven Strategies for Suppressing Postoperative Tumor Recurrence. This schematic illustrates three pivotal nanomedical strategies that synergistically counteract recurrence by targeting residual disease and the immunosuppressive tumor microenvironment within the surgical cavity.
Lisong Pang, Zhuomin Wang, Zhenhua Jin, Ahmed H. Ghonaim, Hengcheng Zhang, Xinyu You, Jinzhuo Ning, Jiaqing Cao, Yang Liu   +8 more
wiley   +1 more source

Artificial intelligence in healthcare: Clinical decision making algorithms, evidence-based applications, future insights, and beyond. [PDF]

J Int Med Res
Huang Z, Zhu J.
europepmc   +1 more source