Results 41 to 50 of about 858,528 (292)
The value of patients' expectation on breast oncoplastic surgery
, 2014 Breast Unit Barretos Cancer Hospital Sao Paulo Co-ordinator - Breast Oncoplastic Training CenterSchool of Medicine of Botucatu PGDGOM Sao ...
Vieira, Rene A. C. +1 more
core +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Updates in endocrine therapy for metastatic breast cancer
Cancer Biology & Medicine, 2022 Endocrine therapy (ET) remains the mainstay of treatment for steroid hormone receptor-positive, human epidermal growth factor 2 (HER2)-negative metastatic breast cancer (MBC).
Poorni M. Manohar, Nancy E. Davidson
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Translational OncologyThere is increasing evidence that the intake of specific dietary supplements may reduce the risk of breast cancer. Pterostilbene (PTE), a naturally occurring stilbene compound that is widely found in berries, induced pyroptosis in EMT6 and 4T1 cells in a
Xiaoxia Huang +5 more
doaj +1 more source
Chemokine axes in breast cancer: factors of the tumor microenvironment reshape the CCR7-driven metastatic spread of luminal-A breast tumors [PDF]
Journal of Leukocyte Biology, 2016 Abstract Chemokine axes have been shown to mediate site-specific metastasis in breast cancer, but their relevance to different subtypes has been hardly addressed. Here, with the focus on the CCR7-CCL21 axis, patient datasets demonstrated that luminal-A tumors express relatively low CCR7 levels compared with more aggressive disease ...
Weitzenfeld P. +7 more
openaire +3 more sources
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Frontiers in PharmacologySmall extracellular vesicles (sEVs) play a pivotal regulatory role in intercellular communication within breast cancer, coordinating tumor growth, microenvironment remodeling, immune modulation, and therapeutic response.
Jiaxiu Li, Hengzheng Cheng, Xiao Liu
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Topical topics of CDK4/6 inhibitors in adjuvant treatment of early breast cancer [PDF]
Waike lilun yu shijianHormone receptor positive/human epidermal growth factor receptor 2 negative (HR+/HER2-) breast cancer is the predominant molecular subtype. However, even after completion of standard adjuvant endocrine therapy, patients of this subtype continue to face a
XU Jiayan, ZHU Siji
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