Results 121 to 130 of about 397,872 (340)

The relationship between microscopic margins of resection and the risk of local recurrence in patients with breast cancer treated with breast-conserving surgery and radiation therapy [PDF]

, 1994
Stuart J. Schnitt, Anthony Abner, Rebecca Gelman, James L. Connolly, Abram Recht, Rosemary B. Duda, Timothy J. Eberlein, Kathleen Mayzel, Barbara Silver, Jay R. Harris   +9 more
openalex   +1 more source

If it does not help, it might hurt: Pharmacodynamics of a second IVIg course in Guillain–Barré syndrome

Annals of Clinical and Translational Neurology, EarlyView.
Abstract Objectives Intravenous immunoglobulin (IVIg) is an effective treatment for Guillain–Barré syndrome (GBS), but recovery varies between patients. This study aims to evaluate the pharmacokinetics (PK) and pharmacodynamics (PD) of a single and a second IVIg dose (SID) in patients with GBS.
Sander J. van Tilburg, Ruth Huizinga, Krista Kuitwaard, Sebastiaan D.T. Sassen, Christa Walgaard, Pieter A. van Doorn, Bart C. Jacobs, Birgit C.P Koch   +7 more
wiley   +1 more source

MAZ-mediated up-regulation of BCKDK reprograms glucose metabolism and promotes growth by regulating glucose-6-phosphate dehydrogenase stability in triple-negative breast cancer

Cell Death and Disease
Tumour metabolic reprogramming is pivotal for tumour survival and proliferation. Investigating potential molecular mechanisms within the heterogeneous and clinically aggressive triple-negative breast cancer (TNBC) subtype is essential to identifying ...
Yan Li, Yuxiang Lin, Yali Tang, Meichen Jiang, Xiaobin Chen, Hanxi Chen, Qian Nie, Jinqiao Wu, Xin Tong, Jing Li, Liuwen Yu, Jialin Hou, Wenhui Guo, Lili Chen, Minyan Chen, Jie Zhang, Shuhai Lin, Fangmeng Fu, Chuan Wang   +18 more
doaj   +1 more source

Exploring causal effects of hormone- and radio-treatments in an observational study of breast cancer using copula-based semi-competing risks models [PDF]

arXiv
Breast cancer patients may experience relapse or death after surgery during the follow-up period, leading to dependent censoring of relapse. This phenomenon, known as semi-competing risk, imposes challenges in analyzing treatment effects on breast cancer and necessitates advanced statistical tools for unbiased analysis.
arxiv  

Perioperative Antibiotic Prophylaxis for Herniorrhaphy and Breast Surgery [PDF]

, 1990
Richard Platt, Dori F. Zaleznik, Cyrus C. Hopkins, E. Patchen Dellinger, A. W. Karchmer, Charles S Bryan, John F. Burke, Matthew A. Wikler, Susan Marino, Kathleen F. Holbrook   +9 more
openalex   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Intra-operative tumour margin evaluation in breast-conserving surgery with deep learning [PDF]

arXiv
A positive margin may result in an increased risk of local recurrences after breast retention surgery for any malignant tumour. In order to reduce the number of positive margins would offer surgeon real-time intra-operative information on the presence of positive resection margins.
arxiv  

RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer

Advanced Biology, EarlyView.
Analysing RhoA and Rac1 protein levels in Colorectal cancer (CRC) samples under mechanical strain highlights their potential as diagnostic markers. Monitoring their activity could offer valuable insights into how cancer spreads, paving the way for new approaches to better understand and diagnose colorectal cancer.
Sharda Yadav, Sanjaya KC, Mark A. T. Blaskovich, Cu‐tai Lu, Alfred K Lam, Nam‐Trung Nguyen   +5 more
wiley   +1 more source

The Regulation of Trace Metal Elements in Cancer Ferroptosis

Advanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang, Yuanyuan Xue, Lei Chang, Xuena Zhu, Wenjun Liu, Tingbo Liang   +5 more
wiley   +1 more source

Endoscopic fiber-coupled diamond magnetometer for cancer surgery [PDF]

arXiv
Interoperative measurements using magnetic sensors is a valuable technique in cancer surgery for finding magnetic tracers. Here we present a fiber-coupled nitrogen-vacancy (N-V) center magnetometer capable of detecting iron oxide suspension (MagTrace from Endomagnetics Ltd.) used in breast cancer surgeries.
arxiv