Results 171 to 180 of about 3,910,197 (311)

Increasing trends in the use of breast-conserving surgery in California [PDF]

open access: bronze, 2000
Cyllene R. Morris   +3 more
openalex   +1 more source

Microphysiological Systems in Cancer Research: Advancing Immunotherapy through Tumor Microenvironment‐Integrated Organ‐On‐Chip Models

open access: yesAdvanced Therapeutics, EarlyView.
Emerging microphysiological systems reproduce the spatial, biochemical, and cellular complexity of the tumor microenvironment, surpassing 2D cultures and murine models. By integrating patient‐derived tumors, perfusable vasculature, and immune trafficking, these organ‐on‐chip platforms reveal mechanisms of immune evasion, predict therapeutic responses ...
Fabiana Moresi   +5 more
wiley   +1 more source

The Utility of Erector Spinae Plane Blocks in Breast Surgery: A Practical Review. [PDF]

open access: yesPlast Reconstr Surg Glob Open
Raborn Macdonald L   +3 more
europepmc   +1 more source

Aesthetic Breast Surgery and Concomitant Procedures: Incidence and Risk Factors for Major Complications in 73,608 Cases

open access: yesAesthetic surgery journal, 2017
Varun Gupta   +6 more
semanticscholar   +1 more source

Copper and Iron‐Based Metal‐Organic Frameworks for Synergistic Cancer Phototherapies: Recent Advances, Challenges, and Future Prospects

open access: yesAdvanced Therapeutics, EarlyView.
The graphical abstract illustrates the combined effect of PTT and PDT using metal‐organic frameworks (MOFs) in a cancer treatment model. Tumor‐bearing mice are irradiated with different laser lights, which activate the MOF nanoparticles within cancer cells. The MOFs produce reactive oxygen species through PDT, while PTT elevates the temperature to kill
Kayalvizhi Samuvel Muthiah   +5 more
wiley   +1 more source

Twenty-year follow-up of a randomized study comparing breast-conserving surgery with radical mastectomy for early breast cancer.

open access: yesNew England Journal of Medicine, 2002
U. Veronesi   +7 more
semanticscholar   +1 more source

SMYD3 Promotes Immune Evasion in Clear Cell Renal Cell Carcinoma via SREBP1‐Mediated Transactivation of CD47

open access: yesAdvanced Science, EarlyView.
Cancer cell‐intrinsic SMYD3 orchestrates an immunosuppressive microenvironment and impairs the response to PD‐1 blockade by reprogramming immune cells landscape in the tumor microenvironment of clear cell renal cell carcinoma (ccRCC). The immunomodulatory function of SMYD3 is mediated via the SREBP1/CD47 pathway.
Zhengfang Liu   +14 more
wiley   +1 more source

ST6GAL1‐Mediated Sialylation Stabilizes PD‐L1 and Drives Immunosuppressive Tumor Microenvironment in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
ST6GAL1 plays a critical role in tumor progression and immune regulation in colorectal cancer (CRC). Its depletion significantly suppresses the malignant phenotype of CRC cells and enhances the efficacy of anti‐PD‐L1 therapy. High ST6GAL1 expression promotes an immune‐activated tumor microenvironment (TME), characterized by increased infiltration of ...
Ximo Xu   +15 more
wiley   +1 more source

Patient decision aids in breast surgery and breast reconstruction reduce decisional conflict: a systematic review and meta-analysis. [PDF]

open access: yesBreast Cancer Res Treat
Williams T   +8 more
europepmc   +1 more source

Exploring AAV‐Mediated Gene Therapy for Inner Ear Diseases: from Preclinical Success to Clinical Potential

open access: yesAdvanced Science, EarlyView.
Current preclinical studies of AAV‐mediated gene therapy explore different strategies based on the characteristics of inner ear diseases. For genetic hearing loss, approaches include the replacement of a “good gene,” removal of a “bad gene,” or direct correction of mutations through base editing.
Fan Wu   +7 more
wiley   +1 more source

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