Single‐cell sequencing reveals stress‐programmed immune states driving TNFα–TNFR2–mediated Treg activation and therapy resistance in breast cancer, while targeting this axis restores antitumor immunity. ABSTRACT The tumor microenvironment (TME) harbors diverse immune cell states that shape therapeutic outcomes in breast cancer.
Zhibo Shao +18 more
wiley +1 more source
TriCON: A Carbon‐Based Triple‐Modal Nanoplatform for Pancreatic Cancer Therapy
We developed TriCON, a triple‐modality nanotherapeutic platform, to treat pancreatic ductal adenocarcinoma (PDAC) by synergizing gene editing, chemotherapy, and immunotherapy. TriCON utilizes CRISPR/Cas9 to target the poliovirus receptor (PVR), combined with nano‐encapsulated doxorubicin and checkpoint blockade. This approach achieved significant tumor
Xinyu Peng +9 more
wiley +1 more source
Comparing the analgesic efficacy of liposomal bupivacaine versus bupivacaine for postoperative pain management in breast surgery: protocol for a systematic review and meta-analysis. [PDF]
Jiao B, Xu X, Yan C, Xu J, Chen C.
europepmc +1 more source
Automatic Gas Control Mode Versus Manual Minimal-flow and Medium-flow Anaesthesia in Breast Surgery: A Comparative Study. [PDF]
Çeviker G +8 more
europepmc +1 more source
Single-stage delayed hybrid reconstruction after failed implant-based breast surgery using the pedicled thoracodorsal artery perforator flap: a report of three cases. [PDF]
Shah R +3 more
europepmc +1 more source
The Utility of Erector Spinae Plane Blocks in Breast Surgery: A Practical Review. [PDF]
Raborn Macdonald L +3 more
europepmc +1 more source
Insurer and patient costs for repeat breast surgery after initial lumpectomy for breast cancer. [PDF]
Wing SE +5 more
europepmc +1 more source

