Results 61 to 70 of about 4,208,685 (408)

High leukocyte mitochondrial DNA copy number contributes to poor prognosis in breast cancer patients

BMC Cancer, 2023
Background Compelling evidence has indicated a significant association between leukocyte mitochondrial DNA copy number (mtDNAcn) and prognosis of several malignancies in a cancer-specific manner.
Wenzhe Zhang, Songping Lin, Bangwei Zeng, Xiaobin Chen, Lili Chen, Minyan Chen, Wenhui Guo, Yuxiang Lin, Liuwen Yu, Jialin Hou, Yan Li, Shengmei Li, Xuan Jin, Weifeng Cai, Kun Zhang, Qian Nie, Hanxi Chen, Jing Li, Peng He, Qindong Cai, Yibin Qiu, Chuan Wang, Fangmeng Fu   +22 more
doaj   +1 more source

BREAST-Q Measurement of the Patient Perspective in Oncoplastic Breast Surgery: A Systematic Review

Plastic and Reconstructive Surgery, Global Open, 2018
Background: Since BREAST-Q was developed in 2009, it has been widely used by clinicians and researchers to capture information regarding health-related quality of life (HRQoL) and patient satisfaction related to breast surgery.
L. Liu, O. Branford, Sinead Mehigan
semanticscholar   +1 more source

Breast surgery for metastatic breast cancer [PDF]

Cochrane Database of Systematic Reviews, 2014
Metastatic breast cancer is not a curable disease, but women with metastatic disease are living longer. Surgery to remove the primary tumour is associated with an increased survival in other types of metastatic cancer. Breast surgery is not standard treatment for metastatic disease, however several recent retrospective studies have suggested that ...
Tosello, Giuliano, Torloni, Maria R, Salani, Bruna, Neeman, Teresa, Riera, Rachel   +4 more
openaire   +6 more sources

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

The psychological influence of the diagnosis of breast cancer on therapeutic options selection [PDF]

, 2017
The therapeutic management decision-making process for breast cancer is complex, and is influenced by multiple factors including patient age, comorbidities, ethnicity, education, and availability of immediate or delayed reconstruction options.
Balalau, Cristian, Cozma, Cristina, Jecan, Radu, Popescu, Bogdan, Scaunasu, Razvan V., Voiculescu, Stefan   +5 more
core   +6 more sources

Atypical Ductal Hyperplasia at the Margin of Lumpectomy Performed for Early Stage Breast Cancer: Is there Enough Evidence to Formulate Guidelines? [PDF]

, 2012
Background. Negative margins are associated with a reduced risk of ipsilateral breast tumor recurrence (IBTR) in women with early stage breast cancer treated with breast conserving surgery (BCS).
Baker, Jennifer L, Blair, Sarah L, Hasteh, Farnaz   +2 more
core   +3 more sources

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Acute changes in clinical breast measurements following bra removal:implications for surgical practice [PDF]

, 2015
BackgroundStable measurement of breast position is crucial for objective pre-operative planning and post-operative evaluation. In clinical practice, breast measures are often taken immediately following bra removal.
Brown, Nicola, Loveridge, Amy, Mills, Chris, Scurr, Joanna   +3 more
core   +3 more sources

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

Mammograms in cosmetic breast surgery [PDF]

Indian Journal of Plastic Surgery, 2005
ABSTRACTMammograms are necessary as preoperative preparation for breast surgery in certain patients. There is a definite need for mammograms preoperatively in patients over 40 who should be obtaining mammograms on an annual basis. Under the age of 40 mammograms are up to the discretion of the surgeon.
openaire   +6 more sources