Results 91 to 100 of about 143,046 (261)

Sustained Delivery of a Shingles Subunit Vaccine Overcomes Age‐Related Declines in Humoral and Cellular Immunity Relative to Shingrix

Advanced Science, EarlyView.
Sustained delivery of a shingles subunit vaccine from an injectable polymer–nanoparticle hydrogel enhanced the potency, durability, and breadth of immune responses in aged mice while minimizing inflammatory cytokine production and reactogenicity. This strategy decouples immunogenicity from reactogenicity and offers a promising approach to improve ...
Ye Eun Song, Jerry Yan, Ben S. Ou, Olivia M. Saouaf, Noah Eckman, E. A. Appel   +5 more
wiley   +1 more source

A re-testing range is recommended for ¹³C- and ¹⁴C-urea breath tests for Helicobacter pylori infection in China. [PDF]

Gut Pathog, 2021
Wang X, Zhang S, Chua EG, He Y, Li X, Liu A, Chen H, Wise MJ, Marshall BJ, Sun D, Li X, Tay CY.   +11 more
europepmc   +1 more source

Multiscale Coupling From Mastication to Retronasal Aroma Perception: The PG‐DTCFN Model and Multiphysics Simulation

Advanced Science, EarlyView.
Using grilled lamb skewers as a model system, this work builds a multiscale coupling framework from oral processing to retronasal aroma perception, reveals dual‐kinetic release patterns and Electroencephalogram‐characterized central encoding features, and proposes an interpretable physics‐guided deep learning model validated by multiphysics simulation,
Che Shen, Xiongfeng He, Zihao Li, Zidong Chen, Jiajin Sun, Xinyu Jiang, Yunhui Zhang, Lizhang Wu, Ran Wang, Jingnan Lu, Bo Wang, Kezhou Cai, Baocai Xu   +12 more
wiley   +1 more source

(Fe4N/GaN)@GC: A Bifunctional Electrocatalyst for High‐Performance Rechargeable Zinc‐Air Batteries

Advanced Science, EarlyView.
This work demonstrates that an unprecedented Fe4N/GaN heterostructure, stabilized by a graphitized carbon shell, induces interfacial charge redistribution and optimizes oxygen‐intermediate adsorption, enabling highly efficient bifunctional ORR/OER electrocatalysis for rechargeable zinc‐air batteries.
Xin‐Yuan Wei, Sai‐Sai Xie, Xia‐Li Ding, Yuan‐Qi Zhai, Sen Yu, Xiang‐Quan Hu, Rongqian Wu, Jintao Lu, Yan‐Zhen Zheng   +8 more
wiley   +1 more source

A Dual‐Modal Wearable PPG Smartwatch with AI‐Enhanced Correction for High‐Accuracy and Continuous AF Burden Assessment

Advanced Science, EarlyView.
ABSTRACT Atrial fibrillation (AF) increases the risk of stroke and heart failure, yet accurate quantification of AF burden in daily life remains difficult. Although smartwatch photoplethysmography (PPG) supports continuous monitoring, complex rhythms and signal noise can impair burden estimation.
Song Zuo, Jinglei Wang, Xin Wang, Han Feng, Yize Zhao, Fadong Li, Shaobin Wei, Le Zhou, Zixu Zhao, Songjie Chen, Xiangyi Kong, Jue Wang, Liu He, Shijun Xia, Xin Li, Junmeng Zhang, Xiaoxia Liu, Xueyuan Guo, Ning Zhou, Songnan Li, Chenxi Jiang, Ribo Tang, Caihua Sang, Deyong Long, Xin Du, Jianzeng Dong, Wenwu Zhu, Changsheng Ma   +27 more
wiley   +1 more source

European guideline on indications, performance and clinical impact of ¹³ C-breath tests in adult and pediatric patients: An EAGEN, ESNM, and ESPGHAN consensus, supported by EPC. [PDF]

United European Gastroenterol J, 2021
Keller J, Hammer HF, Afolabi PR, Benninga M, Borrelli O, Dominguez-Munoz E, Dumitrascu D, Goetze O, Haas SL, Hauser B, Pohl D, Salvatore S, Sonyi M, Thapar N, Verbeke K, Fox MR, European 13C-breath test group.   +16 more
europepmc   +1 more source

Exhaled breath volatiles for asthma diagnosis: discovery and validation in untreated but symptomatic patients

Scientific Reports
Approximately 30% of people with a clinical diagnosis of asthma do not have the condition. Exhaled volatile organic compounds (VOCs) hold promise for non-invasive asthma testing; however, discovery of breath biomarkers is confounded by high biological ...
Agnieszka Turlo, Waqar Ahmed, Ran Wang, Iain White, Maxim Wilkinson, Robin Curnow, Kamila Schmidt, Miriam Bennett, Angela Simpson, Clare Murray, David C. Wedge, Stephen J. Fowler   +11 more
doaj   +1 more source

Small intestinal bacterial overgrowth and intestinal methanogen overgrowth in gastrointestinal malignancies

Contemporary Oncology
Small intestinal bacterial overgrowth (SIBO) is defined by an abnormal proliferation of colon-specific bacteria in the small intestine, whereas intestinal methanogen overgrowth (IMO) manifests with an increase of methane-producing archaea, specifically ...
Aleksandra Mechlińska, Katarzyna Frąckiewicz, Katarzyna Gładyś-Cieszyńska, Dagmara Buczek, Rafał Dziadziuszko   +4 more
doaj   +1 more source

High‐Density E. Coli Cultivation Arrays for Combinatorial Drug Testing With Subsequent Lipid Profiling by MALDI‐MS

Advanced Science, EarlyView.
High‐throughput antibiotic cross‐gradient assays on microdroplet arrays. A multichannel printhead together with five pressure regulators forms droplet arrays of up to 20 832 droplets within 25 minutes. Each droplet contains unique concentrations of antibiotics, allowing to moniture a vast spectrum of bacterial repsonses over night. The bacterial growth
M. Breitfeld, C. L. Dietsche, F‐L. Born, I. Onipko, L. Blaase, P. S. Dittrich   +5 more
wiley   +1 more source

Highly Repeatable Fibrous Crack‐Based Strain Sensor for Multichannel Continuous Tremor Monitoring in Parkinson's Disease and Essential Tremor

Advanced Science, EarlyView.
This study proposes a patch‐type tremor monitoring system based on high‐repeatable fibrous crack‐based strain sensor, capable of simultaneously measuring tremor in multiple locations such as thumb, index, and wrist. Through clinical trials involving Parkinson's disease and essential tremor patients, the proposed system demonstrates its potential as a ...
Chiwon Song, Chan Park, Juyoun Lee, Hojoong Kim, Jeongbeom Kang, Byeongjun Lee, Cheoljeong Park, Jungmin Kim, Haran Lee, Yoon Jae Lee, Min‐Kyung Yeo, Woon‐Hong Yeo, Seong J. Cho   +12 more
wiley   +1 more source