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PGE2 Supplementation of Oocyte Culture Media Improves the Developmental and Cryotolerance Performance of Bovine Blastocysts Derived From a Serum-Free in vitro Production System, Mirroring the Inner Cell Mass Transcriptome

open access: yesFrontiers in Cell and Developmental Biology, 2021
The culture media used throughout the in vitro production (IVP) of bovine embryos remain complex. The serum added to culture media in order to improve embryo development negatively impacts the cryotolerance of blastocysts.
Gilles Charpigny   +19 more
doaj   +1 more source

DMRT1 is a testis-determining gene in rabbits and is also essential for female fertility

open access: yeseLife, 2023
DMRT1 is the testis-determining factor in several species of vertebrates, but its involvement in mammalian testes differentiation, where SRY is the testis-determining gene, remains ambiguous.
Emilie Dujardin   +10 more
doaj   +1 more source

Ancestry-inclusive dog genomics challenges popular breed stereotypes

open access: yesScience, 2022
Behavioral genetics in dogs has focused on modern breeds, which are isolated subgroups with distinctive physical and, purportedly, behavioral characteristics.
Kathleen Morrill   +24 more
semanticscholar   +1 more source

Importance of Windows of Exposure to Maternal High-Fat Diet and Feto-Placental Effects: Discrimination Between Pre-conception and Gestational Periods in a Rabbit Model

open access: yesFrontiers in Physiology, 2021
Context and Aim: Lipid overnutrition in female rabbits, from prepuberty, leads to impaired metabolism (dyslipidemia and increased adiposity) and follicular atresia, and, when continued during gestation, affects offspring phenotype with intrauterine ...
Delphine Rousseau-Ralliard   +16 more
doaj   +1 more source

Pressurized intra-peritoneal aerosol chemotherapy (PIPAC): increased intraperitoneal pressure does not affect distribution patterns but leads to deeper penetration depth of doxorubicin in a sheep model

open access: yesBMC Cancer, 2021
Background Pressurized Intra-Peritoneal Aerosol Chemotherapy (PIPAC) is an innovative treatment against peritoneal carcinomatosis. Doxorubicin is a common intra-venous chemotherapy used for peritoneal carcinomatosis and for PIPAC.
Myriam Mimouni   +14 more
doaj   +1 more source

Involving Animal Models in Uterine Transplantation

open access: yesFrontiers in Surgery, 2022
BackgroundAbsolute uterine factor infertility affects 0. 2% women of childbearing age around the world. Uterine transplantation (UTx) is a promising solution for many of them since the first birth from UTx was described by the Swedish team in 2014.
Angeline Favre-Inhofer   +28 more
doaj   +1 more source

H3K27me3 at pericentromeric heterochromatin is a defining feature of the early mouse blastocyst

open access: yesScientific Reports, 2022
Early mouse development is characterized by structural and epigenetic changes while cells progress towards differentiation. At blastocyst stage, the segregation of the three primordial lineages is accompanied by establishment of differential patterns of ...
Mélanie Pailles   +7 more
doaj   +1 more source

Identification of the Inner Cell Mass and the Trophectoderm Responses after an In Vitro Exposure to Glucose and Insulin during the Preimplantation Period in the Rabbit Embryo

open access: yesCells, 2022
The prevalence of metabolic diseases is increasing, leading to more women entering pregnancy with alterations in the glucose-insulin axis. The aim of this work was to investigate the effect of a hyperglycemic and/or hyperinsulinemic environment on the ...
Romina Via y Rada   +8 more
doaj   +1 more source

Preimplantation factor modulates trophoblastic invasion throughout the decidualization of human endometrial stromal cells

open access: yesReproductive Biology and Endocrinology, 2021
Background Successful human embryo implantation requires the differentiation of endometrial stromal cells (ESCs) into decidual cells during a process called decidualization.
Esther Dos Santos   +8 more
doaj   +1 more source

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