Results 51 to 60 of about 680,154 (292)

Quantitative determination of fatty acids in the University of Vermont\u27s CREAM herd followed over the course of six months [PDF]

open access: yes, 2014
Holstein and Jersey cows were used to determine how the fatty acid profile of their milk differed with regard to breed of cow and season over the course of six months.
O\u27Day, John F, III
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Comparative analysis of the physical and phenotypic traits of native cattle (Bos indicus) in the Tarai region of North Bihar for conservation [PDF]

open access: yesVeterinary World
Background and Aim: The evaluation of the phenotypic and morphological characteristics of indigenous breeds may help to frame breeding policies and plans to implement breed conservation and improvement programs to increase the efficiency of the native ...
Krishna Mohan   +2 more
doaj   +1 more source

Prediction of the relationship between body weight and body condition score in sheep [PDF]

open access: yes, 2003
During the whole production cycle it is important to monitor the energy balance and to quantify body reserve changes of the ewes. This can be done, both in experimental settings and in the field, by estimating the body condition score (BCS) of the ewes ...
Boe, Filippo, Cannas, Antonello
core  

New Breed

open access: yesJournal of Human-Technology Relations, 2023
In The New Breed: How to Think About Robots (2021), Kate Darling argues that to understand our future with robots a lot can be learned from studying our relationship with animals. The animal analogy raises important new questions, can help to design our futures with robots, and helps to develop an approach to robot rights.
Grommé, Francisca   +2 more
openaire   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Gemeentediakonaat – Nuut gedink

open access: yesVerbum et Ecclesia, 2023
The diaconate of the congregation – Considered anew. From the earliest times, the content given to the diaconate of the congregation varied greatly from denomination to denomination.
Gert Breed
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Gyrinidae of Wisconsin, With a Key to Adults of Both Sexes and Notes on Distribution and Habitat [PDF]

open access: yes, 2017
More than 25,000 adult gyrinids that include 24 species were studied from all areas of Wisconsin. Dineutus discolor, Gyrinus aeneolus, G. analis, G. bifarius, and G. marginellus are lotic; D. assimilis, G. aquiris, G. confinis, and G. dichrous apparently
Hilsenhoff, William L
core   +3 more sources

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