Results 91 to 100 of about 1,600,675 (344)
Molecular Oncology, EarlyView.In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton +17 more
wiley +1 more source
Frontiers in Sustainable Food SystemsOrange-fleshed sweet potato (OFSP) is a promising crop in combating vitamin A deficiencies (VAD) in sub-Saharan Africa (SSA)‘s vulnerable populations and its adoption directly impacts potential benefits across the value chains.
Idrissou Ahoudou +6 more
doaj +1 more source
POTATO VARIETIES PROMISING FOR BREEDING TARGETED AT COMMERCIAL TRAITS
Труды по прикладной ботанике, генетике и селекции, 2018 The article presents the results of studying VIR’s potato collection. Following such study, the best cultivars of potato are recommended as source material for breeding programs targeted at basic commercial traits, such as high yield, starch content ...
L. I. Kostina, O. S. Kosareva
doaj +1 more source
M3.5 ‐ Organic plant breeding in a systems‐based approach and integration of organic plant breeding in value chain partnerships [PDF]
, 2019 Developing organic breeding is a key challenge for the organic sector. It is necessary to better adapt varieties to the specific needs of the organic sector (disease resistance, taste, weed suppressing ability, etc).
Messmer, Monika M. +2 more
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Molecular Oncology, EarlyView.Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho +11 more
wiley +1 more source
Magnetic Resonance Imaging Characteristics of Hereditary Polymyositis in the Dutch Kooiker Dog
PetsBackground: Hereditary immune-mediated polymyositis has been reported in the Kooiker dog breed, associated with a 39 kb deletion and low penetrance.
Yvet Opmeer +3 more
doaj +1 more source
Research results on robusta coffee breeding in Vietnam
Vietnam Journal of Science, Technology and Engineering, 2017 In the research and development of coffee trees in Vietnam, particularly breeding is one of the most important activities and always prioritized by the Government.
Viet Ha Phan
doaj +1 more source
Use of DNA-based genetic markers in plant breeding [PDF]
, 2005 Genetic markers have been used since the beginnings of plant breeding, but the concept of linkage and recently the availability of molecular markers have offered new and powerful tools that can help to perform the traditional tasks of selection or that ...
Backes, Gunter
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Selective Breeding to Improve Productive and Reproductive Performances and Survivability of Indigenous Sakini Chicken [PDF]
, 2020 Indigenous chickens are quite popular in Family Poultry Production System (FPPS) in Nepal, but are constrained with their low productive performance. The present study evaluated the productive and reproductive performance of Sakini chicken in different ...
Bhattarai, N. (Nirajan) +4 more
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A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source