Results 71 to 80 of about 1,563,321 (361)
Molecular Oncology, EarlyView.In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton +17 more
wiley +1 more source
Brazilian Archives of Biology and Technology, 2007 The aim of this study was to identify plants of the IAPAR-59 and Tupi IAC 1669-33 coffee cultivars with less defeated resistance genes by the rust races present at IAPAR (Londrina, Paraná State, Brazil) using test-crosses.
Gustavo Hiroshi Sera +6 more
doaj +1 more source
Molecular breeding of sugarcane using linkage disequilibrium maps and quantitative trait alleles : [Abstract W247] [PDF]
, 2009 Sugarcane breeding generally involves forms of recurrent selection using overlapping generations of parent genotypes, with the number of parents used in the order of 100 to 400, depending on the size of the breeding program.
Butterfield, Mike +3 more
core
Molecular Oncology, EarlyView.Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho +11 more
wiley +1 more source
The integration of ‘omic’ disciplines and systems biology in cattle breeding
Animal, 2011 Enormous progress has been made in the selection of animals, including cattle, for specific traits using traditional quantitative genetics approaches.
D.P. Berry +6 more
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Seasonal decline in breeding performance of the Kelp Gull Larus dominicanus [PDF]
, 2008 The effects of timing of breeding on reproductive parameters of Kelp Gulls Larus dominicanus were studied in Patagonia, Argentina, during 1998 and 1999.
Garcia Borboroglu, Jorge Pablo +3 more
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Environmental conditions during early life accelerate the rate of senescence in a short-lived passerine bird [PDF]
, 2015 Environmental conditions experienced in early life may shape subsequent phenotypic traits including life history. We investigated how predation risk caused by domestic cats (Felis silvestris catus) and local breeding density affected patterns of ...
Balbontín Arenas, Javier +1 more
core +2 more sources
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Advances and prospects of super rice breeding in China
Journal of Integrative Agriculture, 2017 Super rice breeding in China has been very successful over the past 3 decades, and the Chinese government has made great efforts to support breeding and cultivation of both conventional and hybrid super rice.
Liang TANG, Zheng-jin XU, Wen-fu CHEN
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