Results 81 to 90 of about 478,542 (302)

Capital and income breeding : the role of food supply [PDF]

, 2014
This work was funded by the Natural Environment Research Council (grant number 2003/00616). A. I. Houston and J. M. McNamara were supported by Leverhulme Trust fellowships; A. I.
Stephens, P.A., Boyd, I.L., Stephens, Philip, McNamara, John M., Boyd, Ian L., Harding, Karin C., Harding, Karin C.,, McNamara, John, Stephens, Philip A., Boyd, Ian, Houston, Alasdair I., Houston, A.I., Houston, Alasdair, Harding, K.C., McNamara, J.M.   +14 more
core   +1 more source

Three-dimensional model of DEMO-FNS facility considering neutronics and radiation shield problems

Heliyon, 2019
Recent neutronics studies of blankets for tokamak-based demonstration fusion neutron source (DEMO-FNS) showed a crucial influence of coolant composition on the transmutation rate of transuranic elements and tritium breeding in the system.
A.V. Zhirkin, B.V. Kuteev
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Data integration for decision making in wheat breeding [PDF]

, 2011
Plant breeding is a production process requiring the creation of germplasm through taking existing successful cultivars and crossing them with new parental lines with agronomic and quality attributes of interest.
Diepeveen, Dean
core  

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Cross-section sensitivity of tritium breeding in fusion reactor blankets [PDF]

, 1973
ion; San Diego, California, USA (16 Apr 1974). The objective of the present study is the identification of crosssection uncertainties which might produce uncertainties of the order of several percent in the tritium breeding ratio in fusion reactor ...
Tobias, M., Steiner, D.
core   +1 more source

Numerical Investigation and Analytical Modeling of MHD Pressure Drop in Lead–Lithium Flows Within Rectangular Ducts Under Variable Magnetic Field for Nuclear Fusion Reactors

Journal of Nuclear Engineering
The breeding blanket is a key component of tokamaks, primarily responsible for extracting heat from fusion reactions and for tritium breeding, which is essential to ensure a fusion reactor’s fuel self-sufficiency.
Silvia Iannoni, Gianluca Camera, Marcello Iasiello, Nicola Bianco, Giuseppe Di Gironimo   +4 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source