Results 91 to 100 of about 476,906 (298)
A theoretical and practical analysis of the optimum breeding system for perennial ryegrass [PDF]
, 2011 peer-reviewedThe goal of plant breeding is to effectively and efficiently select for the best phenotypes leading to the development of improved cultivars. The objectives for this review are to describe and critically evaluate breeding methods appropriate
Conaghan, Patrick, Casler, M.D.
core +1 more source
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Agricultural Genetics and Plant Breeding in Early Twentieth-Century Italy [PDF]
, 2013 This thesis is about plant breeding in Early 20th-Century Italy. The stories of the two most prominent Italian plant-breeders of the time, Nazareno Strampelli and Francesco Todaro, are used to explore a fragment of the often-neglected history of Italian ...
Iori, Luca <1983>
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Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
The Breeding Ecology of Homed Puffins Fratercula comiculata in Alaska. [PDF]
, 2001 The Horned Puffin {Fratercula corniculata) is one of three North Pacific puffin species. Horned Puffins almost always nest amongst boulders and in rock crevices.
Harding, Ann Marie Aglionby
core
Nuclear FusionAccurate modeling of particle transport within fusion blankets is essential for predicting performance metrics such as heat deposition and the tritium breeding ratio (TBR).
Jin Whan Bae +4 more
doaj +1 more source
Accident-tolerant hybrid ceramics for fusion breeding blanket
Materials & DesignIn a water-cooled ceramic breeding blanket for fusion reactors, hydrogen gas generation by steam oxidation of metallic Be compounds (i.e. neutron multiplier) in a loss-of-coolant accident (LOCA) raises major safety concerns. Li–Be hybrid ceramics has a potential to reduce hydrogen generation significantly, however, the stable compositions and ...
Keisuke Mukai +3 more
openaire +2 more sources
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
DEMO Breeding Blanket Concepts in EUROfusion work package breeding blanket (WPBB)
, 2021 Zhou, Guangming +1 more
openaire +3 more sources
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source