Results 71 to 80 of about 476,906 (298)

Turning the heat up on independent culling in crop breeding

, 2022
Most grain crops are sensitive to heat stress during anthesis which causes substantial reductions in grain yield, and heat stress tolerance (HST) is therefore an important trait for selection in crop breeding programmes during the 21st century.
Li, Li, Cowling, Wallace
core  

ITER Water Cooled Lithium Lead Test Blanket System transient thermal-hydraulic analysis

Nuclear Fusion
The planned experimental activities of the ITER Test Blanket Module (TBM) program will be a key step in understanding the physics and technologies required for tritium breeding blankets, which are essential for achieving tritium self-sufficiency in a ...
Tommaso Glingler, Gianfranco Caruso, Danilo Nicola Dongiovanni, Salvatore D’Amico, Italo Ricapito, Paul Wouters, Francesca Fantini, Joelle Elbez-Uzan, Sandrine Rosanvallon, Matteo D’Onorio   +9 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Conceptual radiation shielding design of the integrated breeding test facility at KFE

Nuclear Engineering and Technology
The Integrated Breeding Test Facility (IBTF) is being developed by Korea Institute of Fusion Energy to assess the long-term performance of breeding blankets under continuous irradiation environment.
Hyoseong Gwon, Dohyun Kim, Seonghee Hong, Mu-Young Ahn   +3 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Searching for exotic scalars at fusion reactors

Journal of High Energy Physics
Part of the energy created in deuterium-tritium fusion reactors is carried away from plasma by a high-intensity neutron flux, which is then absorbed by the reactor’s inner walls.
Chaja Baruch, Patrick J. Fitzpatrick, Tony Menzo, Yotam Soreq, Sokratis Trifinopoulos, Jure Zupan   +5 more
doaj   +1 more source

Tritium Extraction from Liquid Blankets of Fusion Reactors via Membrane Gas–Liquid Contactors

Journal of Nuclear Engineering
The exploitation of fusion energy in tokamak reactors relies on efficient and reliable tritium management. The tritium needed to sustain the deuterium–tritium fusion reaction is produced in the Li-based blanket surrounding the plasma chamber, and ...
Silvano Tosti, Luca Farina
doaj   +1 more source

Progress in EU Breeding Blanket design and integration

Fusion Engineering and Design, 2018
In Europe (EU), in the frame of the EUROfusion consortium activities, four Breeding Blanket (BB) concepts are being developed with the aim of fulfilling the performances required by a near-term fusion power demonstration plant (DEMO) in terms of tritium self-sufficiency and electricity production.
Cismondi, F., Boccaccini, L. V., Aiello, G., Aubert, J., Bachmann, C., Barrett, T., Barucca, L., Bubelis, E., Ciattaglia, S., Del Nevo, A., Diegele, E., Gasparotto, M., Di Gironimo, G., Di Maio, P. A., Hernandez, F., Federici, G., Fernández-Berceruelo, I., Franke, T., Froio, A., Gliss, C., Keep, J., Loving, A., Martelli, E., Maviglia, F., Moscato, I., Mozzillo, R., Poitevin, Y., Rapisarda, D., Savoldi, L., Tarallo, A., Utili, M., Vala, L., Veres, G., Zanino, R.   +33 more
openaire   +6 more sources

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Capital and income breeding : the role of food supply [PDF]

, 2014
This work was funded by the Natural Environment Research Council (grant number 2003/00616). A. I. Houston and J. M. McNamara were supported by Leverhulme Trust fellowships; A. I.
Stephens, P.A., Boyd, I.L., Stephens, Philip, McNamara, John M., Boyd, Ian L., Harding, Karin C., Harding, Karin C.,, McNamara, John, Stephens, Philip A., Boyd, Ian, Houston, Alasdair I., Houston, A.I., Houston, Alasdair, Harding, K.C., McNamara, J.M.   +14 more
core   +1 more source