Results 61 to 70 of about 476,906 (298)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Inverse Kinematics and Statics-Based Motion Planning of a 7-DoF Transporter for DEMO-Type Breeding Blankets

Machines
Future fusion power plants like DEMO must be remotely maintained for safety, including breeding blankets (BBs) weighing up to 180 t. The BB vertical transporter (BBVT), a crane-like redundant robot with 7 joints, has been previously designed for handling
Hjalte Durocher, Christian Bachmann, Rocco Mozzillo, Günter Janeschitz, Xuping Zhang   +4 more
doaj   +1 more source

Avian Cholera emergence in Arctic-nesting northern Common Eiders: using community-based, participatory surveillance to delineate disease outbreak patterns and predict transmission risk

Ecology and Society, 2016
Emerging infectious diseases are a growing concern in wildlife conservation. Documenting outbreak patterns and determining the ecological drivers of transmission risk are fundamental to predicting disease spread and assessing potential impacts on ...
Samuel A. Iverson, Mark R. Forbes, Manon Simard, Catherine Soos, H. Grant Gilchrist   +4 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Variation of neutron yield from a titanium-tritide target during deuterium beam bombardment. [PDF]

, 1986
In the laboratory simulation of D-T fusion breeder blankets 14 MeV neutrons are produced by the bombardment of a titanium-tritide target with deuterium ions using accelerating voltages up to 500 keV and beam currents ranging from micro to milliamperes.
Dalton, AW, Woodley, HJ
core  

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

CGIAR Excellence in Breeding Platform - Plan of Work and Budget 2019 [PDF]

, 2019
The CGIAR Excellence in Breeding Platform has been established to enable change within CGIAR breeding networks toward higher rates of genetic gain and scale of impact per dollar invested.
CGIAR Excellence in Breeding Platform
core  

Neutronics experiment of tritium breeding in supercritical CO2 cooled lithium-lead blanket mock-up by D–T neutron irradiation

Nuclear Fusion
The tritium breeding capacity of fusion blankets is a critical factor in achieving tritium self-sufficiency in fusion reactors. Current designs for tritium production in blankets are based on neutronics simulations, whose accuracy requires experimental ...
Qiankun Shao, Qingjun Zhu, Zuocong Liu, Tianyi Liu, Jie Bao, Songlin Liu   +5 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source