Results 131 to 140 of about 407,600 (313)

Deep scoping: a breeding strategy to preserve, reintroduce and exploit genetic variation. [PDF]

Theor Appl Genet, 2021
Vanavermaete D, Fostier J, Maenhout S, De Baets B.   +3 more
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Overcoming Reproductive Compromise Under Heat Stress in Wheat: Physiological and Genetic Regulation, and Breeding Strategy. [PDF]

Front Plant Sci, 2022
Li M, Feng J, Zhou H, Najeeb U, Li J, Song Y, Zhu Y.   +6 more
europepmc   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Correction: Microbiome-driven breeding strategy potentially improves beef fatty acid profile benefiting human health and reduces methane emissions. [PDF]

Microbiome, 2022
Martínez-Álvaro M, Mattock J, Auffret M, Weng Z, Duthie CA, Dewhurst RJ, Cleveland MA, Watson M, Roehe R.   +8 more
europepmc   +1 more source

Environment classification for upland rice production region in Brazil. [PDF]

, 2016
The upland rice (UR) cropped area in Brazil has decreased in the last decade. A portion of this can be attributed to the UR breeding program strategy adopted since the 1980s, according to which direct grain selection is targeted primarily to the most ...
HEINEMANN, A. B.
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Breeding Strategy Shapes the Composition of Bacterial Communities in Female Nile Tilapia Reared in a Recirculating Aquaculture System. [PDF]

Front Microbiol, 2021
Abdelhafiz Y, Fernandes JMO, Larger S, Albanese D, Donati C, Jafari O, Nedoluzhko AV, Kiron V.   +7 more
europepmc   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

FEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman, Jessica Haines, Connie Pritchard, Stephen Rutherford, Nigel Francis   +4 more
wiley   +1 more source

Designing the best breeding strategy for Coffea canephora: Genetic evaluation of pure and hybrid individuals aiming to select for productivity and disease resistance traits. [PDF]

PLoS One, 2021
Alkimim ER, Caixeta ET, Sousa TV, Gois IB, Lopes da Silva F, Sakiyama NS, Zambolim L, Alves RS, Resende MDV.   +8 more
europepmc   +1 more source