Results 91 to 100 of about 766,120 (259)
Estimation of genetic parameters for melanoma in the Old Kladruber horse
The aim of this study was to assess the prevalence of melanoma to investigate a possible genetic variation of this trait in the Old Kladruber horse.
L. Vostrý +4 more
doaj +1 more source
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
THE SOCIAL VALUE OF PUBLIC INVESTMENT IN CANADIAN WHEAT BREEDING RESEARCH [PDF]
The level and distribution of the social benefits from public investment in Canadian wheat breeding research and extension activities are examined for the period 1946 to 1979. In addition, average and marginal rates of return are calculated.
Peterson, Willis L., Zentner, Robert P.
core +1 more source
Breeding for improved tuber quality in greater yam (Dioscorea alata L.) [PDF]
Yams constitute an important staple food in tropical and subtropical regions. Dioscorea alata is one of the major cultivated species with a wide geographical distribution. It is currently second to D. rotundata in terms of production volume.
Arnau, Gemma +7 more
core
Stability of Aberdeen Angus breeding values in the Czech Republic from 1997 to 2007
We predict the stability of breeding values (BVs) for direct effect (DE) and maternal effect (ME) for live weights at 210 days of age in the entire population of purebred Aberdeen Angus cattle in the Czech Republic according to an increase of progeny ...
J. Ducháček +5 more
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Testing water-soluble carbohydrate QTL effects in perennial ryegrass (Lolium perenne L.) by marker selection [PDF]
Water-soluble carbohydrates (WSC) are an important factor determining the nutritional value of grass forage and development of genetic markers for selection of WSC traits in perennial ryegrass would benefit future breeding programmes.
Dolstra, O. +3 more
core +3 more sources
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
The potential of Manitoba chokecherry as a source of high natural antioxidants [PDF]
Consumption of fruits and vegetables is shown to be beneficial for protecting health and preventing some chronic diseases such as cancer, cardiovascular disease, and stroke.
Arnold W. Hydamaka +4 more
core +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source

