Results 91 to 100 of about 773,903 (310)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Estimation of genetic parameters for melanoma in the Old Kladruber horse
Czech Journal of Animal Science, 2012 The aim of this study was to assess the prevalence of melanoma to investigate a possible genetic variation of this trait in the Old Kladruber horse.
L. Vostrý +4 more
doaj +1 more source
Breeding for improved tuber quality in greater yam (Dioscorea alata L.) [PDF]
, 2018 Yams constitute an important staple food in tropical and subtropical regions. Dioscorea alata is one of the major cultivated species with a wide geographical distribution. It is currently second to D. rotundata in terms of production volume.
Arnau, Gemma +7 more
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Evaluation of Naked Barley Landraces for Agro-morphological Traits [PDF]
, 2020 Naked barley (Hordeum vulgare var. nudum L.) is a traditional, culturally important, climate-resilient winter cereal crop of Nepal. Evaluation of the naked barely genotypes for yield and disease is fundamental for their efficient utilization in plant ...
Ghimire, K. H. (Krishna) +2 more
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Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Stability of Aberdeen Angus breeding values in the Czech Republic from 1997 to 2007
Czech Journal of Animal Science, 2011 We predict the stability of breeding values (BVs) for direct effect (DE) and maternal effect (ME) for live weights at 210 days of age in the entire population of purebred Aberdeen Angus cattle in the Czech Republic according to an increase of progeny ...
J. Ducháček +5 more
doaj +1 more source
Seabird metapopulations: searching for alternative breeding habitats [PDF]
, 2009 Today, many seabird species nest in port areas, which are also necessary for human economic activity. In this paper, we evaluate, using a metapopulation model, the possibilities for creating alternative breeding sites for the Common Tern (Sterna hirundo)
Jochem, R. +5 more
core +3 more sources
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Accuracy of genomic selection in a rice synthetic population developed for recurrent selection. [PDF]
, 2013 Genomic selection is a promising breeding strategy for rapid improvement of complex traits. We investigated the accuracy of genomic estimate breeding values (GEBV) through cross validation in a synthetic population (SP) of broad genetic diversity ...
Ahmadi, Nourollah +5 more
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