Results 211 to 220 of about 6,365,112 (258)

Boundary‐Dependent Sleep–Wake Dysregulation in Idiopathic Hypersomnia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Idiopathic hypersomnia (IH) presents with excessive daytime sleepiness (EDS) despite apparently preserved nocturnal sleep, challenging traditional models of hypersomnolence based on sleep loss or fragmentation. We aimed to test the hypothesis that EDS in IH reflects excessive stabilization of the sleep state, consistent with ...
Samantha Mombelli, Karine Lacourse, Hélène Blais, Anne‐Sophie Deshaies‐Rugama, Cynthia Thompson, Alex Desautels, Jacques Montplaisir, Milan Nigam, Christophe Moderie, Boshra Khajehpiri, Catherine Duclos, Jean Marc Lina, Julie Carrier, Nadia Gosselin   +13 more
wiley   +1 more source

Alzheimer's Disease Biomarkers Measured by Capillary Blood Collection Versus Venous Plasma and Cerebrospinal Fluid

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Blood biomarkers are increasingly critical for non‐invasive Alzheimer's Disease (AD) diagnostics and research but typically require on‐site processing. Remote point‐of‐care collection methods could enhance biomarker testing in clinical and research settings.
Sara Ho, Ziling Shen, Alexandria Lewis, Megha Patel, Anny Zheng, Gianna Proscino, Thaovy Ho, Jiangxia Wang, Marilyn Albert, Abhay Moghekar   +9 more
wiley   +1 more source

Clinical Impact of MGMT Promoter Methylation in IDH‐Mutant Gliomas: Influence of Threshold Selection and Clinical Confounding

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background The clinical relevance of MGMT promoter methylation in IDH‐mutant gliomas remains controversial in the era of molecular classification. We aimed to systematically evaluate its clinical relevance by integrating quantitative assessment, cutoff exploration, and adjustment for clinical confounding.
Haihui Jiang, Linxi Cao, Xiaodong Chen, Siqi Tong, Qinghui Zhu, Jun Yang, Song Lin, Yong Cui   +7 more
wiley   +1 more source

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Evaluation of the breeding value of sires in the breeding reproducer of the Kholmogory breed of cattle

Legal regulation in veterinary medicine, 2023
Estimates of the breeding value of producers and breeding stock of cattle use various information and analytical models and statistical methods, including the determination of the breeding value of animals using the BLUP methodology and the BLUP AM methodology, for the subsequent transition to predictive genomic SNP selection.
V. Ak. Olontsev, P. Iv. Ukolov, O. G. Sharaskina   +2 more
openaire   +1 more source

THE ADAPTIVE VALUE OF CATTLE IN THE BREEDING OF AYRSHIRE BREED

Genetika i razvedenie zhivotnyh, 2019
In the stables and pasture system, the success of the formation and development of herds on new farms is determined by the adaptive response and viability of cattle obtained in different countries and breeding systems, which was the purpose of the work. The object of the research was a herd of Ayrshire cattle, originally formed by heifers from 15 farms
N. Sivkin, N. Strekozov
openaire   +1 more source

On the computation of breeding values

1990
A model and estimation procedure is presented to estimate breeding values. Algorithms for Sparse QR-factorization on the CRAY X/MP are derived and implemented. Finally an adapted ordering is found, which has some advantages compared with minimum degree ordering.
openaire   +2 more sources

A Framework for Prediction of Breeding Value

1990
Inferences in a univariate normal linear model with two components of variance are discussed from a Bayesian perspective. When variances are known, three scenarios are considered: unknown “nuisance” parameters (β) and breeding values (u), unknown β and known u, and unknown u and known β.
D. Gianola, S. Im, F. W. Macedo
openaire   +1 more source

The effect of culling on breeding values

2020
Culling is inevitable in breeding trials. It removes individuals with undesirable traits but also introduces bias in breeding value estimation since we cannot ensure the population normality assumption. Here a stochastic simulation was used to study the impact of culling on the precision of breeding value estimation.
openaire   +2 more sources

Smart breeding driven by big data, artificial intelligence, and integrated genomic-enviromic prediction

Molecular Plant, 2022
Fan Qian Qian, Rajeev Kumar Varshney, Huihui Li   +2 more
exaly  

Selection of dairy sheep breeds using breeding values

26. Savjetovanje uzgajivača ovaca i koza u Republici Hrvatskoj: Zbornik predavanja
Centar za stočarstvo (CS) i Centar za kontrolu kvalitete stočarskih proizvoda (CKKSP) kao sastavnice Hrvatske agencije za poljoprivredu i hranu (HAPIH) provode veliki broj aktivnosti u sektoru ovčarstva i kozarstva. Većina njih, osnova je uzgojno-selekcijskog rada, za čije je provođenje HAPIH ovlašten od strane Ministarstva poljoprivrede, šumarstva i ...
Špehar, Marija, Kasap, Ante
openaire