Results 1 to 10 of about 108,497 (68)

Дизайн искусственных полиэпитопных Т-клеточных иммуногенов для создания профилактических и терапевтических вакцин [PDF]

open access: yesПисьма в Вавиловский журнал генетики и селекции, 2023
Сергей Иванович Бажан начал работать в «Векторе» в 1975 г. по личному приглашению академика Л.С. Сандах- чиева и стал одним из основоположников новых научных направлений организации. Все без исключения, кому посчастли- вилось учиться у него, работать с
Л.И. Карпенко
doaj   +1 more source

Развитие сибирской школы математической (системной) биологии [PDF]

open access: yesПисьма в Вавиловский журнал генетики и селекции, 2023
В статье описан вклад Сергея Ивановича Бажана в развитие методов компьютерного моделирования сложных биологических систем. Химико-кинетический метод моделирования, предложенный С.И. Бажаном и его коллегой В.А. Лихош- ваем во время работы в ФБУН ГНЦ ВБ «
Н.А. Колчанов   +3 more
doaj   +1 more source

Genetic contribution of breast cancer genes in women of black African origin

open access: yesFrontiers in Genetics, 2023
Breast cancer (BC) is an increasing public health issue worldwide. BC incidence and mortality rates are rising in transitioning countries in Africa, with the most rapid increase occurring in Sub-Saharan Africa (SSA).
Rokhaya Ndiaye   +3 more
doaj   +1 more source

The genetic puzzle of a SOD1-patient with ocular ptosis and a motor neuron disease: a case report

open access: yesFrontiers in Genetics, 2023
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease with a complex genetic architecture, showing monogenic, oligogenic, and polygenic inheritance.
Veria Vacchiano   +15 more
doaj   +1 more source

MicroRNA breed and parent-of-origin effects provide insights into biological pathways differentiating cattle subspecies in fetal liver

open access: yesFrontiers in Genetics, 2023
Introduction: MicroRNAs (miRNAs) play a crucial role in regulating gene expression during key developmental processes, including fetal development.
Callum MacPhillamy   +5 more
doaj   +1 more source

Causal analysis of the gut microbiota in differentiated thyroid carcinoma: a two-sample Mendelian randomization study

open access: yesFrontiers in Genetics, 2023
Objective: Numerous studies have highlighted an association between the gut microbiota (GM) and thyroid tumors. Employing Mendelian randomization methodology, we seek to elucidate the causal link between the gut microbiota and thyroid neoplasms.Methods ...
Zheng Quan   +3 more
doaj   +1 more source

Karyotype diversity in the genus Nysius Dallas, 1852 (Hemiptera, Heteroptera, Lygaeidae) is much greater than you might think [PDF]

open access: yesComparative Cytogenetics, 2023
We studied the karyotype and chromosomal distribution of 18S rDNA clustered in nucleolar organizer regions (NORs) in Nysius graminicola (Kolenati, 1845), belonging to the subfamily Orsillinae (Lygaeidae).
Natalia V. Golub   +2 more
doaj   +3 more sources

Novel enhancer mediates the RPL36A-HNRNPH2 readthrough loci and GLA gene expressions associated with fabry disease

open access: yesFrontiers in Genetics, 2023
Fabry disease (FD) is a rare genetic condition caused by mutations in the GLA gene, located on the X chromosome in the RPL36-HNRNPH2 readthrough genomic region. This gene produces an enzyme called alpha-galactosidase A (α-Gal A). When the enzyme does not
Mohammed A. Al-Obaide   +3 more
doaj   +1 more source

Systematic Analysis of Long Non-Coding RNA Genes in Nonalcoholic Fatty Liver Disease

open access: yesNon-Coding RNA, 2022
The largest solid organ in humans, the liver, performs a variety of functions to sustain life. When damaged, cells in the liver can regenerate themselves to maintain normal liver physiology. However, some damage is beyond repair, which necessitates liver
Mirolyuba Ilieva   +6 more
doaj   +1 more source

The role of cellular polyploidy in the regeneration of the cirrhotic liver in rats and humans [PDF]

open access: yesComparative Cytogenetics
Polyploidy is a condition in which a cell has multiple diploid sets of chromosomes. Two forms of polyploidy are known. One of them, generative polyploidy, is characteristic of all cells of the organism, while the other form develops only in some somatic ...
Natalia N. Bezborodkina   +2 more
doaj   +3 more sources

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