Results 1 to 10 of about 162,755 (120)

Integration of morpho-physico-biochemical traits with SSR and SRAP markers for characterization of castor genotypes of Indian origin

Oil Crop Science, 2022
Castor (Ricinus communis L.) is an important tropical oilseed crop, whose oil has versatile, practical value, especially in industries. The present study aimed to estimate the nature and magnitude of variability in the castor germplasm concerning yield ...
Akhila S. R, Sushil Kumar, Amar A. Sakure, Dipak A. Patel, Mukesh P. Patel   +4 more
doaj   +1 more source

Tobacco smoking and risks of >470 diseases in China: a prospective cohort study

Lancet Public Health, 2022
Background Tobacco smoking is estimated to account for >1 million annual deaths in China, and the epidemic continues to increase in men. Large nationwide prospective studies linked to different health records can help assess periodically disease burden ...
K. Chan, N. Wright, D. Xiao, Yu Guo, Yiping Chen, H. Du, Ling Yang, I. Millwood, P. Pei, Junzheng Wang, I. Turnbull, S. Gilbert, D. Avery, C. Kartsonaki, Canqing Yu, Junshi Chen, J. Lv, R. Clarke, R. Collins, R. Peto, Liming Li, Chen Wang, Zhengming Chen   +22 more
semanticscholar   +1 more source

A Randomized, Controlled Comparison of NCX 470 (0.021%, 0.042%, and 0.065%) and Latanoprost 0.005% in Patients With Open-angle Glaucoma or Ocular Hypertension: The Dolomites Study

Journal of glaucoma, 2022
Précis: NCX 470 0.042% and 0.065% were statistically superior in intraocular pressure (IOP) lowering to latanoprost 0.005%, and NCX 470 0.021% was noninferior. All NCX 470 concentrations were safe and well tolerated.
T. Walters, Angela C. Kothe, J. Boyer, D. Usner, Krisol Lopez, B. Duquesroix, R. Fechtner, Tomas Navratil   +7 more
semanticscholar   +1 more source

Berberine Suppresses Mice Depression Behaviors and Promotes Hippocampal Neurons Growth Through Regulating the miR-34b-5p/miR-470-5p/BDNF Axis

Neuropsychiatric Disease and Treatment, 2021
Background Berberine has been found to inhibit the progression of depression disorder, but its specific mechanism is still unclear. MicroRNA (miRNA) is considered to play an important role in the progression of depression.
Yuhua Zhan, Jiyang Han, Jing Xia, Xumei Wang   +3 more
semanticscholar   +1 more source

Characterization of transposable elements within the Bemisia tabaci species complex

Mobile DNA, 2022
Background Whiteflies are agricultural pests that cause negative impacts globally to crop yields resulting at times in severe economic losses and food insecurity. The Bemisia tabaci whitefly species complex is the most damaging in terms of its broad crop
Juan Paolo A. Sicat, Paul Visendi, Steven O. Sewe, Sophie Bouvaine, Susan E. Seal   +4 more
doaj   +1 more source

Helicobacter pylori CagA Induces Cortactin Y-470 Phosphorylation-Dependent Gastric Epithelial Cell Scattering via Abl, Vav2 and Rac1 Activation

Cancers, 2021
Simple Summary Various microbial pathogens target the actin-binding protein cortactin to promote their own uptake, proliferation and spread, and exhibit proposed roles in human cancerogenesis. We aimed to study the molecular mechanisms of how the gastric
Nicole Tegtmeyer, A. Harrer, K. Rottner, S. Backert   +3 more
semanticscholar   +1 more source

Gene interaction analysis of psoriasis in Chinese Han population

Molecular Genetics & Genomic Medicine, 2022
Background/aims Psoriasis is a chronic immune‐mediated inflammatory skin disease characterized by excessive proliferation of keratinocytes. It has a strong genetic predisposition; gene‐gene interactions are important genetic models for common diseases ...
Qiongqiong Xu, Xiaodong Zheng, Yiwen Mao, Weiwei Chen, Shirui Chen, Hui Zhang, Qi Zhen, Bao Li, Liang Yong, Huiyao Ge, Yafen Yu, Ruixue Zhang, Lu Cao, Hui Cheng, Wenjun Wang, Liangdan Sun   +15 more
doaj   +1 more source

Identification of a novel heterozygous SOX9 variant in a Chinese family with congenital heart disease

Molecular Genetics & Genomic Medicine, 2022
Background Previous studies of individuals with hereditary or sporadic congenital heart disease (CHD) have provided strong evidence for a genetic basis for CHD.
Li Gong, Chunyan Wang, Haiyang Xie, Jun Gao, Tengyan Li, Shenggui Qi, Binbin Wang, Jing Wang   +7 more
doaj   +1 more source

Identification of Neoantigens and Construction of Immune Subtypes in Prostate Adenocarcinoma

Frontiers in Genetics, 2022
Background: Messenger ribonucleic acid (mRNA) vaccine has been considered as a potential therapeutic strategy and the next research hotspot, but their efficacy against prostate adenocarcinoma (PRAD) remains undefined.
Yukui Gao, Guixin Wang, Yanzhuo Chen, Mingpeng Zhang, Wenlong Gao, Zhiqun Shang, Yuanjie Niu   +6 more
doaj   +1 more source

A nonsense mutation in MME gene associates with autosomal recessive late‐onset Charcot–Marie–Tooth disease

Molecular Genetics & Genomic Medicine, 2022
Background The genetic cause for the majority of patients with late‐onset axonal form of neuropathies have remained unknown. In this study we aimed to identify the causal mutation in a family with multiple affected individuals manifesting a range of ...
Zeinab Jamiri, Rana Khosravi, Mohammad Mehdi Heidari, Ebrahim Kiani, Javad Gharechahi   +4 more
doaj   +1 more source