Results 41 to 50 of about 202,349 (91)

The retrohoming of linear group II intron RNAs in Drosophila melanogaster occurs by both DNA ligase 4-dependent and -independent mechanisms. [PDF]

open access: yesPLoS Genetics, 2012
Mobile group II introns are bacterial retrotransposons that are thought to have invaded early eukaryotes and evolved into introns and retroelements in higher organisms.
Travis B White, Alan M Lambowitz
doaj   +1 more source

The date of interbreeding between Neandertals and modern humans. [PDF]

open access: yesPLoS Genetics, 2012
Comparisons of DNA sequences between Neandertals and present-day humans have shown that Neandertals share more genetic variants with non-Africans than with Africans.
Sriram Sankararaman   +4 more
doaj   +1 more source

Transcriptome Analysis of Newly Emerged Honeybees Exposure to Sublethal Carbendazim During Larval Stage

open access: yesFrontiers in Genetics, 2018
There are increasing concerns regarding the impact of agrochemical pesticides on non-target organisms. Pesticides could cause honeybee abnormal development in response to neurotoxins such as neonicotinoid.
Kang Wang   +9 more
doaj   +1 more source

A functional variant in microRNA-146a promoter modulates its expression and confers disease risk for systemic lupus erythematosus. [PDF]

open access: yesPLoS Genetics, 2011
Systemic lupus erythematosus (SLE) is a complex autoimmune disease with a strong genetic predisposition, characterized by an upregulated type I interferon pathway. MicroRNAs are important regulators of immune homeostasis, and aberrant microRNA expression
Xiaobing Luo   +12 more
doaj   +1 more source

SUMO-targeted ubiquitin ligase, Rad60, and Nse2 SUMO ligase suppress spontaneous Top1-mediated DNA damage and genome instability. [PDF]

open access: yesPLoS Genetics, 2011
Through as yet undefined proteins and pathways, the SUMO-targeted ubiquitin ligase (STUbL) suppresses genomic instability by ubiquitinating SUMO conjugated proteins and driving their proteasomal destruction.
Johanna Heideker   +4 more
doaj   +1 more source

Altered Ca2+ kinetics associated with α-actinin-3 deficiency may explain positive selection for ACTN3 null allele in human evolution. [PDF]

open access: yesPLoS Genetics, 2015
Over 1.5 billion people lack the skeletal muscle fast-twitch fibre protein α-actinin-3 due to homozygosity for a common null polymorphism (R577X) in the ACTN3 gene.
Stewart I Head   +7 more
doaj   +1 more source

A gain-of-function mutation in Tnni2 impeded bone development through increasing Hif3a expression in DA2B mice. [PDF]

open access: yesPLoS Genetics, 2014
Distal arthrogryposis type 2B (DA2B) is an important genetic disorder in humans. However, the mechanisms governing this disease are not clearly understood. In this study, we generated knock-in mice carrying a DA2B mutation (K175del) in troponin I type 2 (
Xiaoquan Zhu   +20 more
doaj   +1 more source

Regulation of adipogenesis by nucelar receptor PPARγ is modulated by the histone demethylase JMJD2C

open access: yesGenetics and Molecular Biology, 2011
A potential strategy to combat obesity and its associated complications involves modifying gene expression in adipose cells to reduce lipid accumulation.
Lizcano Fernando   +2 more
doaj  

Título: Ordenanças [et] prematicas hechas por Sus Altezas sobre los abogados [et] procuradores [et] derechos que han de lleuar alos pleyteantes [et] a los que se ygualaren durante el pleyto [et] las diligencias que han de hazer los abogados [et] procuradores ansi enla corte como enlos juycios particulares [PDF]

open access: yes
Peu d'impr. obtingut dels repertoris. Segons IBE: [Salamanca : Tip. de Nebrija: "Gramática", (Haeb. 470) (d. 26 junio, 1499]). Segons GW: [Salamanca: Drucker von Antonius Nebrissensis, Gramática castellana (GW 2224) (Antonius Nebrissensis?) für] Fernando
Jaén, Fernando de   +1 more
core  

Ritual fragments, tablet concordance KUB XVII 29 - CTH 470

open access: yes, 2015
Transcription of the ritual fragments based on tablet concordance KUB XVII 29 (inventory no. Bo 2424). Emmanuel Laroche translated this text as "Fragments de rituels,” and classified the concordance in the category of Anatolian magic in ritual texts ...
Gonnet-Bağana, Hatice
core   +1 more source

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