Results 51 to 60 of about 162,755 (120)
Frontiers in Genetics, 2018 The commensal yeast Candida albicans is an opportunistic pathogen. In order to successfully colonize or infect the human body, the fungus must adapt to the host’s environmental conditions, such as low oxygen tension (hypoxia), temperature (37°C), and the
Thais F. Bartelli +4 more
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International Journal of Production Economics, 2020 This study investigates the role of supply chain risk management (SCRM) in mitigating the effects of disruptions impacts on supply chain resilience and robustness in the context of COVID-19 outbreak.
Jamal El Baz, Salomée Ruel
semanticscholar +1 more source
Methylation QTLs are associated with coordinated changes in transcription factor binding, histone modifications, and gene expression levels. [PDF]
PLoS Genetics, 2014 DNA methylation is an important epigenetic regulator of gene expression. Recent studies have revealed widespread associations between genetic variation and methylation levels.
Nicholas E Banovich +8 more
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Journal of Veterinary Internal Medicine, 2014 Background Many chemotherapy protocols have been reported for treatment of canine appendicular osteosarcoma (OSA), but outcome comparisons in a single population are lacking.
L. Selmic +4 more
semanticscholar +1 more source
The DSIF subunits Spt4 and Spt5 have distinct roles at various phases of immunoglobulin class switch recombination. [PDF]
PLoS Genetics, 2012 Class-switch recombination (CSR), induced by activation-induced cytidine deaminase (AID), can be divided into two phases: DNA cleavage of the switch (S) regions and the joining of the cleaved ends of the different S regions.
Andre Stanlie +3 more
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Polyglutamine toxicity is controlled by prion composition and gene dosage in yeast. [PDF]
PLoS Genetics, 2012 Polyglutamine expansion causes diseases in humans and other mammals. One example is Huntington's disease. Fragments of human huntingtin protein having an expanded polyglutamine stretch form aggregates and cause cytotoxicity in yeast cells bearing ...
He Gong +8 more
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The retrohoming of linear group II intron RNAs in Drosophila melanogaster occurs by both DNA ligase 4-dependent and -independent mechanisms. [PDF]
PLoS Genetics, 2012 Mobile group II introns are bacterial retrotransposons that are thought to have invaded early eukaryotes and evolved into introns and retroelements in higher organisms.
Travis B White, Alan M Lambowitz
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The date of interbreeding between Neandertals and modern humans. [PDF]
PLoS Genetics, 2012 Comparisons of DNA sequences between Neandertals and present-day humans have shown that Neandertals share more genetic variants with non-Africans than with Africans.
Sriram Sankararaman +4 more
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Frontiers in Genetics, 2018 There are increasing concerns regarding the impact of agrochemical pesticides on non-target organisms. Pesticides could cause honeybee abnormal development in response to neurotoxins such as neonicotinoid.
Kang Wang +9 more
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A functional variant in microRNA-146a promoter modulates its expression and confers disease risk for systemic lupus erythematosus. [PDF]
PLoS Genetics, 2011 Systemic lupus erythematosus (SLE) is a complex autoimmune disease with a strong genetic predisposition, characterized by an upregulated type I interferon pathway. MicroRNAs are important regulators of immune homeostasis, and aberrant microRNA expression
Xiaobing Luo +12 more
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