Results 31 to 40 of about 162,755 (120)

Considering Genetic Heterogeneity in the Association Analysis Finds Genes Associated With Nicotine Dependence

Frontiers in Genetics, 2019
While substantial progress has been made in finding genetic variants associated with nicotine dependence (ND), a large proportion of the genetic variants remain undiscovered. The current research focuses have shifted toward uncovering rare variants, gene-
Xuefen Zhang, Tongtong Lan, Tong Wang, Wei Xue, Xiaoran Tong, Tengfei Ma, Guifen Liu, Qing Lu   +7 more
doaj   +1 more source

Dissecting the Immune Stimulation Promoted by CSF-470 Vaccine Plus Adjuvants in Cutaneous Melanoma Patients: Long Term Antitumor Immunity and Short Term Release of Acute Inflammatory Reactants

Frontiers in Immunology, 2018
As cutaneous melanoma (CM) currently remains with a bleak prognosis, thorough investigation of new treatment options are of utmost relevance. In the phase II/III randomized clinical trial (CASVAC-0401), the repeated immunization of stages IIB-III CM ...
M. Pampena, Holliday Cartar, G. Cueto, E. Levy, P. Blanco, M. M. Barrio, J. Mordoh   +6 more
semanticscholar   +1 more source

Changes in the TCRβ Repertoire and Tumor Immune Signature From a Cutaneous Melanoma Patient Immunized With the CSF-470 Vaccine: A Case Report

Frontiers in Immunology, 2018
The allogeneic therapeutic vaccine CSF-470 has demonstrated a significant benefit over medium-dose IFNα2b in the distant metastasis-free survival for stages IIB–IIC–III cutaneous melanoma patients in a randomized phase II/III clinical trial (CASVAC-0401,
Mariana Aris, A. Bravo, M. Pampena, P. Blanco, Ibel Carri, D. Koile, P. Yankilevich, E. Levy, M. M. Barrio, J. Mordoh   +9 more
semanticscholar   +1 more source

Y-STR Haplogroup Diversity in the Jat Population Reveals Several Different Ancient Origins

Frontiers in Genetics, 2017
The Jats represent a large ethnic community that has inhabited the northwest region of India and Pakistan for several thousand years. It is estimated the community has a population of over 123 million people.
David G. Mahal, David G. Mahal, Ianis G. Matsoukas   +2 more
doaj   +1 more source

The Globin Gene Family in Arthropods: Evolution and Functional Diversity

Frontiers in Genetics, 2020
Globins are small heme-proteins that reversibly bind oxygen. Their most prominent roles in vertebrates are the transport and storage of O2 for oxidative energy metabolism, but recent research has suggested alternative, non-respiratory globin functions ...
Andreas Prothmann, Federico G. Hoffmann, Federico G. Hoffmann, Juan C. Opazo, Juan C. Opazo, Peter Herbener, Jay F. Storz, Thorsten Burmester, Thomas Hankeln   +8 more
doaj   +1 more source

In vitro bactericidal activity of 465–470 nm blue light phototherapy and aminolevulinic acid on Staphylococcus pseudintermedius

Veterinary dermatology (Print), 2018
BACKGROUND Staphylococcus pseudintermedius is the principal pathogen causing bacterial skin infections in dogs. Photodynamic therapy (PDT) involving the combination of light and a topical photosensitizer is used to treat human skin infections.
S. Bae, T. Oh
semanticscholar   +1 more source

Bibliography of studies on hybrid zones of the common shrew chromosome races distributed in Russia

Comparative Cytogenetics, 2013
The common shrew, Sorex araneus Linnaeus, 1758, has become a model species for cytogenetical and evolutionary studies after discovery of extraordinary Robertsonian polymorphism at the within-species level. Development of differential staining techniques (
Rena Nadjafova
doaj   +1 more source

Extracellular Vesicles of Human Periodontal Ligament Stem Cells Contain MicroRNAs Associated to Proto-Oncogenes: Implications in Cytokinesis

Frontiers in Genetics, 2020
The human Periodontal Ligament Stem Cells (hPDLSCs) exhibit self-renewal capacity and clonogenicity potential. The Extracellular Vesicles (EVs) secreted by hPDLSCs are particles containing lipids, proteins, mRNAs, and non-coding RNAs, among which ...
Luigi Chiricosta, Serena Silvestro, Agnese Gugliandolo, Guya Diletta Marconi, Jacopo Pizzicannella, Placido Bramanti, Oriana Trubiani, Emanuela Mazzon   +7 more
doaj   +1 more source

Adaptive Remodeling of the Bacterial Proteome by Specific Ribosomal Modification Regulates Pseudomonas Infection and Niche Colonisation. [PDF]

PLoS Genetics, 2016
Post-transcriptional control of protein abundance is a highly important, underexplored regulatory process by which organisms respond to their environments.
Richard H Little, Lucia Grenga, Gerhard Saalbach, Alexandra M Howat, Sebastian Pfeilmeier, Eleftheria Trampari, Jacob G Malone   +6 more
doaj   +1 more source

A Generic Multivariate Framework for the Integration of Microbiome Longitudinal Studies With Other Data Types

Frontiers in Genetics, 2019
Simultaneous profiling of biospecimens using different technological platforms enables the study of many data types, encompassing microbial communities, omics, and meta-omics as well as clinical or chemistry variables.
Antoine Bodein, Olivier Chapleur, Arnaud Droit, Kim-Anh Lê Cao   +3 more
doaj   +1 more source