FEBS Open Bio, EarlyView.KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura +19 more
wiley +1 more source
On the equivalence between marker effect models and breeding value models and direct genomic values with the Algorithm for Proven and Young. [PDF]
Genet Sel Evol, 2022 Bermann M +4 more
europepmc +1 more source
FEBS Open Bio, EarlyView.In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source
Generating Douglas-fir Breeding Value Estimates Using Airborne Laser Scanning Derived Height and Crown Metrics. [PDF]
Front Plant Sci, 2022 du Toit F +3 more
europepmc +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Verifying the Breeding Value of A Rare Haplotype of Chalk7, GS3, and Chalk5 to Improve Grain Appearance Quality in Rice. [PDF]
Plants (Basel), 2022 Wang D +5 more
europepmc +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
Case Study on Increasing Breeding Value Estimation Reliability of Reproductive Traits in Serbian Highly Prolific Large White and Landrace Sows. [PDF]
Animals (Basel), 2022 Stojiljković N +6 more
europepmc +1 more source
How phagocytic cells kill bacteria: Lessons from a professional killer
FEBS Open Bio, EarlyView.How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley +1 more source
Оценка урожайности перспективных линий сои селекции ФГБНУ «АНЦ «Донской»
Зерновое хозяйство России, 2018 The estimation of productivity of the promising lines of soybean developed by the FSBSI “ARC ‘Donskoy” The article presents the material concerning the estimation of productivity of the promising lines of soybean developed by the FSBSI “ARC ‘Donskoy ...
A. R. Ashiev +3 more
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