Results 61 to 70 of about 268,924 (264)

The relation of GH1, GHR and DGAT1 polymorphisms with estimated breeding values for milk production traits of German Holstein sires

open access: yesCzech Journal of Animal Science, 2008
: We analysed the relations of estimated breeding values (EBV) of 315 German Holstein sires to their genotypes in growth hormone gene (GH1), growth hormone receptor gene (GHR) and acylCoA-diacylglycerol acyltransferase 1 (DGAT1).
E. Hradecká   +4 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

COMBINING ABILITY OF SELECTED DESSERT STRAWBERRY CULTIVARS WITH DIFFERENT FRUIT RIPENING PERIODS

open access: yesActa Scientiarum Polonorum: Hortorum Cultus, 2014
The subjects of the study were the strawberry hybrids of the F1 generation, derived from the crossing made between eight cultivars: ‘Darselect’, ‘Selvik’, ‘Elianny’, ‘Susy’, ‘Salsa’, ‘Albion’, ‘Charlotte’ and ‘Filon’ in an incomplete diallel mating ...
Agnieszka Masny   +2 more
doaj  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

ADAPTIVE CAPACITY AND BREEDING VALUE OF VEGETABLE VARIETIES OF PEAS COLLECTION

open access: yesОвощи России, 2015
Adaptive properties and selection value of vegetable pea collection based on «seed weight per plant» have been studied. The genotypes with high total and specific adaptive capacity, relative stability, and breeding value for multiple purposes have been ...
T. N. Abrosimova, A. N. Fadeeva
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Estimation of the breeding value of sport horses in the Czech Republic

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2004
The performance of 10671 horses in 10911 sport competitions was used to estimate the breeding value of the population of the Czech warm-blooded horses using the Best Linear Unibased Prediction method.
Iva Jiskrová
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

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