Results 51 to 60 of about 268,924 (264)

Genetic evaluation for stillbirth and preweaning mortality in Australian dairy cattle

Journal of Dairy Science
: The welfare of calves is important to both farmers and consumers. Practices that increase the proportion of calves born alive and enable them to thrive through to weaning contribute to improved sustainability.
M.M. Axford, M. Khansefid, M. Haile-Mariam, M.E. Goddard, J.E. Pryce   +4 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Variation and Selection of Growth and Wood Property Traits in Cunninghamia lanceolata Full-sib Families

Guangdong nongye kexue
【Objective】The study aims to prepare new and excellent Cunninghamia lanceolata (Lamb.) Hook germplasm materials and select superior families of C. lanceolata families, thus promoting the breeding process of higher generations of the species.【Method】Ten ...
Rong HUANG, Runhui WANG, Su YAN, Ruping WEI, Guangdi WU, Huiquan ZHENG   +5 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Comparison of models to estimate genetic parameters for scores of competitive sport horse events in the Czech Republic

Czech Journal of Animal Science, 2015
The objective of the present study was to estimate genetic parameters and predict breeding values of sport horses in the Czech Republic using animal model variations.
A. Novotná, A. Svitáková, J. Schmidová   +2 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Genomic breeding value prediction: methods and procedures

Animal, 2010
Animal breeding faces one of the most significant changes of the past decades - the implementation of genomic selection. Genomic selection uses dense marker maps to predict the breeding value of animals with reported accuracies that are up to 0.31 higher than those of pedigree indexes, without the need to phenotype the animals themselves, or close ...
openaire   +4 more sources

Breeding value for type traits in beef cattle in theCzech Republic

Czech Journal of Animal Science, 2005
The type was evaluated in 5 424 young animals of twelve beef breeds. Ten type traits were evaluated: height at sacrum (HS), body length (BL), live weight (LW), front chest width (CW), chest depth (CD), pelvis (P), shoulder muscling (SM), back muscling ...
Z. Veselá, J. Přibyl, P. Šafus, L. Vostrý, K. Šeba, L. Štolc   +5 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source