Results 111 to 120 of about 19,880,174 (348)

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Reinventing quantitative genetics for plant breeding: something old, something new, something borrowed, something BLUE

Heredity, 2020
The goals of quantitative genetics differ according to its field of application. In plant breeding, the main focus of quantitative genetics is on identifying candidates with the best genotypic value for a target population of environments.
R. Bernardo
semanticscholar   +1 more source

Behaviour of kittiwakes during the breeding season: relationships with nest density and breeding success [PDF]

, 2000
Activity budgets for kittiwakes at the nest site were determined for colonies on Tyneside during the pre-laying period in 1996 and for the Skomer Island colony during the pre-laying period in 1998 and for incubation and chick rearing in 1997 and 1998 ...
Nickerson, Michelle
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

COMBINING ABILITY OF SELECTED DESSERT STRAWBERRY CULTIVARS WITH DIFFERENT FRUIT RIPENING PERIODS

Acta Scientiarum Polonorum: Hortorum Cultus, 2014
The subjects of the study were the strawberry hybrids of the F1 generation, derived from the crossing made between eight cultivars: ‘Darselect’, ‘Selvik’, ‘Elianny’, ‘Susy’, ‘Salsa’, ‘Albion’, ‘Charlotte’ and ‘Filon’ in an incomplete diallel mating ...
Agnieszka Masny, Wiesław Mądry, Edward Żurawicz   +2 more
doaj  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

ADAPTIVE CAPACITY AND BREEDING VALUE OF VEGETABLE VARIETIES OF PEAS COLLECTION

Овощи России, 2015
Adaptive properties and selection value of vegetable pea collection based on «seed weight per plant» have been studied. The genotypes with high total and specific adaptive capacity, relative stability, and breeding value for multiple purposes have been ...
T. N. Abrosimova, A. N. Fadeeva
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Estimation of the breeding value of sport horses in the Czech Republic

Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2004
The performance of 10671 horses in 10911 sport competitions was used to estimate the breeding value of the population of the Czech warm-blooded horses using the Best Linear Unibased Prediction method.
Iva Jiskrová
doaj   +1 more source

Breeding value prediction for production traits in layer chickens using pedigree or genomic relationships in a reduced animal model

Genetics Selection Evolution, 2011
BackgroundGenomic selection involves breeding value estimation of selection candidates based on high-density SNP genotypes. To quantify the potential benefit of genomic selection, accuracies of estimated breeding values (EBV) obtained with different ...
A. Wolc, C. Stricker, J. Arango, P. Settar, J. Fulton, N. O'Sullivan, R. Preisinger, D. Habier, R. Fernando, D. Garrick, S. Lamont, J. Dekkers   +11 more
semanticscholar   +1 more source