Results 131 to 140 of about 19,880,174 (348)

Genomic breeding value prediction and QTL mapping of QTLMAS2010 data using Bayesian Methods

BMC Proceedings, 2011
BackgroundBayesian methods allow prediction of genomic breeding values (GEBVs) using high-density single nucleotide polymorphisms (SNPs) covering the whole genome with effective shrinkage of SNP effects using appropriate priors.
Xiaochen Sun, D. Habier, R. Fernando, D. Garrick, J. Dekkers   +4 more
semanticscholar   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Stability of Aberdeen Angus breeding values in the Czech Republic from 1997 to 2007

Czech Journal of Animal Science, 2011
We predict the stability of breeding values (BVs) for direct effect (DE) and maternal effect (ME) for live weights at 210 days of age in the entire population of purebred Aberdeen Angus cattle in the Czech Republic according to an increase of progeny ...
J. Ducháček, J. Přibyl, L. Stádník, L. Vostrý, J. Beran, L. Štolc   +5 more
doaj   +1 more source

The integration of ‘omic’ disciplines and systems biology in cattle breeding [PDF]

, 2010
peer-reviewedEnormous progress has been made in the selection of animals, including cattle, for specific traits using traditional quantitative genetics approaches.
Diskin, Michael G., M.G. Diskin, C.J. Creevey, D. Morris, Mullen, Michael P., D.P. Berry, S. Butler, Morris, Dermot G., M.P. Mullen, Meade, Kieran G, Butler, Stephen T., K.G. Meade, Creevey, Christopher J., Berry, Donagh   +13 more
core   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Seasonality in Offspring Value and Trade-Offs with Growth Explain Capital Breeding

American Naturalist, 2015
The degree to which reproduction is based on reserves (capital breeding) and/or current acquisition (income breeding) drives extensive variation in organism life histories.
M. J. Ejsmond, Ø. Varpe, M. Czarnoleski, J. Kozłowski   +3 more
semanticscholar   +1 more source

Marker-assisted breeding value estimation for mastitis resistance in Finnish Ayrshire cattle

, 2010
Marker-assisted breeding value estimation is expected to increase the accuracy of estimated breeding values, especially for traits with low heritability.
Lidauer, M., Mulder, H. A., J.H. Vilkki, Strandén, Ismo, R.F. Veerkamp, Strandén, I., Vilkki, Johanna H., H.A. Mulder, Veerkamp, R.F., Lidauer, Martin H., Mulder, H.A., Veerkamp, R. F., I. Strandén, Vilkki, J.H., M.H. Lidauer   +14 more
core   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Estimation of breeding value in icelandic sheep [PDF]

Genetics Selection Evolution, 1980
Hallgrímsson S, Jonmundsson JV
openaire   +6 more sources

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source