Results 21 to 30 of about 3,199 (178)

Screening and docking molecular studies of natural products targeting overexpressed receptors HER-2 in breast cancer [PDF]

Archives of Razi Institute
The first cancer to strike a community is breast cancer. Because of its extremely high mitotic activity, breast cancer that tests positive for HER 2 is thought to have a bad prognosis.
Nesrine Lenchi, Naima Maouche, Souad Khemili-Talbi   +2 more
doaj   +1 more source

Impact of suboptimal dosimetric coverage of pretherapeutic 18F-FDG PET/CT hotspots on outcome in patients with locally advanced cervical cancer treated with chemoradiotherapy followed by brachytherapy

Clinical and Translational Radiation Oncology, 2020
Introduction: Areas of high uptake on pre-treatment 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT), denoted as “hotspots”, have been identified as preferential sites of local relapse in locally advanced ...
François Lucia, Vincent Bourbonne, Dorothy Gujral, Gurvan Dissaux, Omar Miranda, Maelle Mauguen, Olivier Pradier, Ronan Abgral, Ulrike Schick   +8 more
doaj   +1 more source

Automatic delineation of functional lung volumes with 68Ga-ventilation/perfusion PET/CT

EJNMMI Research, 2017
Background Functional volumes computed from 68Ga-ventilation/perfusion (V/Q) PET/CT, which we have shown to correlate with pulmonary function test parameters (PFTs), have potential diagnostic utility in a variety of clinical applications, including ...
Pierre-Yves Le Roux, Shankar Siva, Jason Callahan, Yannis Claudic, David Bourhis, Daniel P. Steinfort, Rodney J. Hicks, Michael S. Hofman   +7 more
doaj   +1 more source

Rheumatological features of Whipple disease

Scientific Reports, 2021
Whipple disease (WD) is a rare infectious systemic disease. Rheumatologists are at the frontline of WD diagnosis due to the early rheumatological manifestations. An early diagnosis is crucial, as usual anti-rheumatic drugs, especially TNF inhibitors, may
Alice Tison, Pauline Preuss, Clémentine Leleu, François Robin, Adrien Le Pluart, Justine Vix, Guillaume Le Mélédo, Philippe Goupille, Elisabeth Gervais, Grégoire Cormier, Jean-David Albert, Aleth Perdriger, Béatrice Bouvard, Jean-Marie Berthelot, Nathan Foulquier, Alain Saraux, the network of rheumatologists from the Grand Ouest “VICTOR HUGO”   +16 more
doaj   +1 more source

Sexual well being of breast cancer patients

Nowotwory, 2021
INTRODUCTION: Breast cancer is the most common cancer in women – both in Poland and around the world. In terms of the mortality rate, it subsides brest cancer with lung cancer.
Milena Lachowicz, Joanna Kufel-Grabowska, Mikołaj Bartoszkiewicz, Rodryg Ramlau, Krzysztof Łukaszuk   +4 more
doaj   +1 more source

A critical review on purine and pyrimidine heterocyclic derivatives and their designed molecules in Cancer

Results in Chemistry
This review investigates into the topic of purine and pyrimidine derivatives and their potential as anticancer agents. It thoroughly investigates their efficacy against various types of cancer cells and sheds light on the underlying mechanisms at play ...
Gajanan Sanglikar, Anand Kumar Tengli
doaj   +1 more source

Endocrine therapy‐induced cancer‐related fatigue in hormone‐dependent malignancies: Mechanisms, impact, and management strategies

Precision Medical Sciences, EarlyView.
Multipathway schematic of endocrine therapy–induced cancer‐related fatigue. Endocrine interventions trigger four interacting mechanisms—neuroendocrine dysregulation, systemic inflammation, energy‐metabolic failure, and psycho‐behavioral amplification—that culminate in the multidimensional CRF phenotype.
Jiajing Jiang, Jun Lu, Sen Qin, Ruzhou Chen, Qiuchen Zhang, Lvqi He, Yubei Li, Jingyao Yan   +7 more
wiley   +1 more source

Correlation Between FDG Hotspots on Pre-radiotherapy PET/CT and Areas of HNSCC Local Relapse: Impact of Treatment Position and Images Registration Method

Frontiers in Medicine, 2020
Aim: Several series have already demonstrated that intratumoral subvolumes with high tracer avidity (hotspots) in 18F-flurodesoxyglucose positron-emission tomography (FDG-PET/CT) are preferential sites of local recurrence (LR) in various solid cancers ...
Blandine Truffault, David Bourhis, David Bourhis, Anne Chaput, Jeremie Calais, Jeremie Calais, Philippe Robin, Philippe Robin, Romain Le Pennec, François Lucia, Jean-Christophe Leclère, Dorothy M. Gujral, Dorothy M. Gujral, Pierre Vera, Pierre-Yves Salaün, Pierre-Yves Salaün, Ulrike Schick, Ronan Abgral, Ronan Abgral   +18 more
doaj   +1 more source

Clonal and genomic determinants of e1a2 BCR::ABL1 chronic myeloid leukemia: A Fi‐LMC study

HemaSphere, Volume 10, Issue 8, August 2026.
Abstract The rarer p190 (e1a2) transcript in chronic myeloid leukemia (CML) is associated with atypical presentations; yet, its biological basis remains poorly understood. Using a cohort of 60 patients including 42 chronic phase patients age‐matched 1:1 with 42 e13a2/e14a2 patients in the chronic phase, we investigated the clinical, genomic, and clonal
Benjamin Podvin, Olivier Nibourel, Sandrine Hayette, Valérie Coiteux, Rathana Kim, Lucie Rigolot, Stéphanie Dulucq, Augustin Boudry, Geoffrey Pawlak, Wayne‐Corentin Lambert, Pascale Flandrin‐Gresta, Ivan Sloma, Christophe Roumier, Marie Balsat, Sandrine Loron, Chloé Li, Sandrine Geffroy, Jean‐Michel Cayuela, Françoise Huguet, François‐Xavier Mahon, Franck E. Nicolini, Delphine Réa, Claude Preudhomme, Nicolas Duployez, Catherine Roche‐Lestienne, Fi‐LMC group   +25 more
wiley   +1 more source

Study of down regulation of IL-37 expression in breast cancer tumoral tissues and its association with grade 3 tumor [PDF]

مجله علمی دانشگاه علوم پزشکی کردستان, 2018
Background and Aim: Nowadays, breast cancer is the most common cancer among women in the world. Considering the high prevalence, identification of diagnostic markers can be useful for early diagnosis and cancer management.
Marzieh Ghafari Farsani, Somayeh Reiisi, Maryam Peymani   +2 more
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