Results 131 to 140 of about 9,268 (232)

A Phase I Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Fenebrutinib and Effect on the QT/QTc Interval in Healthy Participants

Clinical and Translational Science, Volume 19, Issue 3, March 2026.
ABSTRACT Fenebrutinib is a Bruton's tyrosine kinase inhibitor under investigation for the treatment of multiple sclerosis. The goal of this study was to investigate the effect of fenebrutinib on cardiac repolarization (QT interval) as well as its safety, tolerability, and pharmacokinetics in healthy participants.
Yan Xu, Sonoko Kawakatsu, Denison Kuruvilla, John N. Ratchford, Qi Qi, Malgorzata Sierzega, Lin Pan, Jiajie Yu   +7 more
wiley   +1 more source

Cytometry-based blood immune cell markers associated with clinical outcomes in systemic sclerosis: protocol for a systematic review. [PDF]

BMJ Open
Souffez M, Dumontet E, Lecureur V, Lescoat A, Ferrant J.   +4 more
europepmc   +1 more source

Understanding the Cause and Diversity of Women's Drink and Drug Driving—A Qualitative Exploration

Drug and Alcohol Review, Volume 45, Issue 3, March 2026.
ABSTRACT Introduction Drink and drug driving continues to pose a significant public health risk, with incidents increasing among women. Building on limited prior research, this study situates women's substance‐impaired driving within a psychosocial and gender‐responsive criminological framework to explore women's experiences with impaired driving ...
Kerry A. Armstrong, Hanna Watling, Taren Mieran, Jessica Marigold   +3 more
wiley   +1 more source

Issue Information

Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.
wiley   +3 more sources

Long‐Term Improvements Following Initial Migraine Response in Eptinezumab‐Treated Participants With Migraine for Whom 2–4 Prior Preventive Treatments Have Failed

European Journal of Neurology, Volume 33, Issue 3, March 2026.
This post hoc analysis of data from the DELIVER trial evaluated long‐term maintenance of early ≥ 50% and ≥ 75% migraine response. For both eptinezumab doses (100 or 300 mg), ≥ 50% or ≥ 75% migraine response over Weeks 1–12 or 1–24 was maintained for the entire 72‐week treatment period for many participants.
Jessica Ailani, Messoud Ashina, Susanne F. Awad, Xin Ying Lee, Line Pickering Boserup, Seema Soni‐Brahmbhatt, Bjørn Sperling, Richard B. Lipton   +7 more
wiley   +1 more source

Progress of coproporphyrin as an endogenous biomarker for transporter-mediated drug-drug interactions. [PDF]

Front Pharmacol
Zhao P, Hu Y, Hu X, Xu Y, Jiang B, Lou H.   +5 more
europepmc   +1 more source

Highly and Lowly Domesticated Endangered Fish From a Conservation Hatchery Diverge in Their Thermal Physiology, Transcriptome, and Methylome

Evolutionary Applications, Volume 19, Issue 3, March 2026.
ABSTRACT Conservation hatcheries aim to produce fish for supplementation of wild populations, but hatchery environments may drive phenotypic divergence from wild fish. These diverged traits may have reduced fitness in the wild, which could compromise wild population sustainability and evolutionary potential, such as in response to climate change. Delta
Joanna S. Griffiths, Amanda J. Finger, Melinda R. Baerwald, Md Moshiur Rahman, Tien‐Chieh Hung, Nann A. Fangue, Andrew Whitehead   +6 more
wiley   +1 more source

Influenza vaccine effectiveness and genetic diversity: insights from end-of-season community surveillance, France, 2024-2025. [PDF]

Emerg Microbes Infect
Clercq A, Blanquart F, Vieillefond V, Visseaux B, Chakra CNA, Nunes MC, Jacques A, Haim-Boukobza S, Wehrle V, Deleglise G, Duret T, Bernard-Stoecklin S, Bercoff DP, Lina B, Rameix-Welti MA, Josset L, Enouf V, Bal A, RELAB study group.   +18 more
europepmc   +1 more source

Co‐Application of Biochar and Organic Matter With Synthetic Fertilisers Improves Nitrogen Use Efficiency, Rice Yield and Benefit–Cost Ratio: A Meta‐Analysis

GCB Bioenergy, Volume 18, Issue 3, March 2026.
Co‐applying biochar and organic matter with synthetic fertilisers improves nitrogen use efficiency, nitrogen uptake, crop yield, and economic return. ABSTRACT Optimising the efficiency of applied nitrogen (N) fertilisers is essential to sustain agricultural systems.
Negar Omidvar, Md Hafiz All Hosen, Michael B. Farrar, Lakmini Dissanayake, Georgette Leah Burns, Shilpi Das, Apurbo Kumar Chaki, Mrinmoy Guha Neogi, M. Wakilur Rahman, Thi Thu Nhan Nguyen, Mehran Rezaei Rashti, Brittany Elliott, Shahla Hosseini Bai   +12 more
wiley   +1 more source

Draft genome sequence data on <i>Streptomyces salinarius</i> MPA0124 isolated from coastal sediments of Pondicherry, India. [PDF]

Data Brief
Prathaban M, Sobanaa M, Kumar SHK, Prathiviraj R, Kiran GS, Selvin J, Dufossé L.   +6 more
europepmc   +1 more source