Results 21 to 30 of about 149,215 (194)

Measuring participant rurality in Web-based interventions

open access: yesBMC Public Health, 2007
Background Web-based health behavior change programs can reach large groups of disparate participants and thus they provide promise of becoming important public health tools.
McKay H Garth   +3 more
doaj   +1 more source

Necrophagy by insects in Oculudentavis and other lizard body fossils preserved in Cretaceous amber

open access: yesScientific Reports, 2023
When a vertebrate carcass begins its decay in terrestrial environments, a succession of different necrophagous arthropod species, mainly insects, are attracted. Trophic aspects of the Mesozoic environments are of great comparative interest, to understand
Mónica M. Solórzano‑Kraemer   +6 more
doaj   +1 more source

Evaluation of critical care burden following traumatic injury from two randomized controlled trials

open access: yesScientific Reports, 2023
Trauma resuscitation practices have continued to improve with new advances targeting prehospital interventions. The critical care burden associated with severely injured patients at risk of hemorrhage has been poorly characterized. We aim to describe the
Insiyah Campwala   +16 more
doaj   +1 more source

Evaluation of Nitrobenzyl Derivatives of Camptothecin as Anti-Cancer Agents and Potential Hypoxia Targeting Prodrugs

open access: yesMolecules, 2018
As part of our initial efforts into developing a tumor-targeting therapy, C-10 substituted derivatives of a camptothecin analog (SN-38) have been synthesized (2-, 3- and 4-nitrobenzyl) for use as potential hypoxia-activated prodrugs and evaluated for ...
Dinghua Liang   +4 more
doaj   +1 more source

COPI complex is a regulator of lipid homeostasis.

open access: yesPLoS Biology, 2008
Lipid droplets are ubiquitous triglyceride and sterol ester storage organelles required for energy storage homeostasis and biosynthesis. Although little is known about lipid droplet formation and regulation, it is clear that members of the PAT (perilipin,
Mathias Beller   +6 more
doaj   +1 more source

Gene editing enables rapid engineering of complex antibiotic assembly lines

open access: yesNature Communications, 2021
Engineering biosynthetic assembly lines is a powerful path to new natural products but is challenging with current methods. Here the authors use CRISPR-Cas9 to exchange subdomains within NRPS to alter substrate selectivity.
Wei Li Thong   +7 more
doaj   +1 more source

Lessons Learned From Transition of an In-Person to a Virtual Randomized Controlled Trial for Weight and Fitness Concerns in Active-Duty Service Members: Survey Study

open access: yesJournal of Medical Internet Research, 2022
BackgroundThis paper describes and discusses the transition of and modifications to a weight management randomized controlled trial among active-duty military personnel from an in-person to a virtual format as a result of the ...
Niloofar Afari   +8 more
doaj   +1 more source

Endovascular rescue of long-term vascular graft implants and need for continuous surveillance

open access: yesJournal of Vascular Surgery Cases and Innovative Techniques, 2018
We present two cases of vascular graft degradation after long-term implantation. In both patients, endovascular techniques were employed to effect continued graft patency and function.
Brian M. Leoce, BS   +3 more
doaj   +1 more source

Development of a rapid serological assay for the diagnosis of strongyloidiasis using a novel diffraction-based biosensor technology. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2014
Strongyloidiasis is a persistent human parasitic infection caused by the intestinal nematode, Strongyloides stercoralis. The parasite has a world-wide distribution, particularly in tropical and subtropical regions with poor sanitary conditions.
Brian J Pak   +11 more
doaj   +1 more source

Identification of candidate B-lymphoma genes by cross-species gene expression profiling. [PDF]

open access: yesPLoS ONE, 2013
Comparative genome-wide expression profiling of malignant tumor counterparts across the human-mouse species barrier has a successful track record as a gene discovery tool in liver, breast, lung, prostate and other cancers, but has been largely neglected ...
Van S Tompkins   +14 more
doaj   +1 more source

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