Results 1 to 10 of about 15,843 (298)

Implantation of nasobiliary drainage in treatment of severe episodes of benign recurrent intrahepatic cholestasis (BRIC) in pediatric patients [PDF]

Clinical & Experimental Hepatology
Benign recurrent intrahepatic cholestasis (BRIC) is a rare genetic disorder characterized by episodes of intrahepatic cholestasis with varying durations and spontaneous resolutions.
Maciej Dądalski, Tetiana Wojciechowska, Joanna Ryżko, Magda Naorniakowska, Joanna Cielecka-Kuszyk, Elżbieta Ciara, Małgorzata Sawilska-Tańska, Joanna Pawłowska   +7 more
doaj   +2 more sources

Genebody specific epigenomic reprogramming of transcriptome promotes immune evasion in oropharyngeal cancer patients in North-Eastern India [PDF]

Clinical Epigenetics
Background Squamous cell carcinoma of oropharynx (OPSCC), a head and neck squamous cell carcinoma (HNSCC) subtype, exhibits a remarkably high incidence rate in the North-Eastern regions of India.
Sahana Ghosh, Indranil Bagchi, Lastborn Marthong, Subrata Patra, Neizekhotuo Brian Shunyu, Srimoyee Ghosh, Arindam Maitra   +6 more
doaj   +2 more sources

Rice PROTEIN L-ISOASPARTYL METHYLTRANSFERASES provides tolerance against sheath blight disease and repairs ALDH and PBZ1 [PDF]

Nature Communications
Protein L-isoaspartyl methyltransferase (PIMT) regulates key seed traits and abiotic stress tolerance in plants by repairing isoaspartyl (isoAsp) damaged proteins.
Shikha Gautam, Nitin Uttam Kamble, Rakesh Kumar Achary, Ravindra Kumar Chandan, Vishal Varshney, Abhijit Hazra, Saroj Laha, Shivangi Mahawar, Sohela Mehandiratta, Sarvanand Singh, Gopaljee Jha, Manoj Majee   +11 more
doaj   +2 more sources

Early blood DNA methylation patterns associated with glycemic progression in a prospective Indian cohort [PDF]

Clinical Epigenetics
Background The prevalence of Type 2 diabetes mellitus (T2DM) is rapidly increasing in India, yet molecular markers that reflect early disease susceptibility remain limited.
Gopika Satheesh, Aneesh K. Asokan, Gadadharan Vijayakumar, Arumugam Rajavelu, Sudha Narayana Rao, Krishnankutty Chandrika Sivakumar, Abdul Jaleel   +6 more
doaj   +2 more sources

Spillovers and contagion between BRIC and G7 markets: New evidence from time-frequency analysis

PLoS ONE, 2022
We examine the time-frequency spillovers, contagion, and pairwise interrelations between the BRIC index and its constituents, and between BRIC and G7 economies.
Samuel Kwaku Agyei, Peterson Owusu Junior, Ahmed Bossman, Emmanuel Asafo-Adjei, Oliver Asiamah, Anokye Mohammed Adam   +5 more
doaj   +3 more sources

Time-frequency domain analysis of investor fear and expectations in stock markets of BRIC economies

Heliyon, 2021
The purpose of this study is to provide insight into the lead-lag relationships between the BRIC stock index and its constituents. In addition, we assess the comovements between the US volatility index (VIX) as a measure of investor uncertainty and fear ...
Peterson Owusu Junior, Anokye M. Adam, Emmanuel Asafo-Adjei, Ebenezer Boateng, Zulaiha Hamidu, Eric Awotwe   +5 more
doaj   +1 more source

Identification of low gamma-glutamyl transferase familial intrahepatic cholestasis - benign recurrent intrahepatic cholestasis in a 22-year-old woman: A case report and literature review

Fides et Ratio, 2022
Introduction: Benign recurrent intrahepatic cholestasis (BRIC) is a rare genetic disorder characterized by recurrent episodes of cholestatic jaundice that may last days to months. It can start at any age, but often in a first decade of life. The syndrome
Marta Kamińska, Jakub Klapaczyński, Urszula Ołdakowska-Jedynak, Dorota Kamińska   +3 more
doaj   +1 more source

Cell cycle arrest and p53 prevent ON-target megabase-scale rearrangements induced by CRISPR-Cas9

Nature Communications, 2023
The CRISPR-Cas9 system has revolutionized our ability to precisely modify the genome and has led to gene editing in clinical applications. Comprehensive analysis of gene editing products at the targeted cut-site has revealed a complex spectrum of ...
G. Cullot, J. Boutin, S. Fayet, F. Prat, J. Rosier, D. Cappellen, I. Lamrissi, P. Pennamen, J. Bouron, S. Amintas, C. Thibault, I. Moranvillier, E. Laharanne, J. P. Merlio, V. Guyonnet-Duperat, J. M. Blouin, E. Richard, S. Dabernat, F. Moreau-Gaudry, A. Bedel   +19 more
doaj   +1 more source

Benign Recurrent Intrahepatic Cholestasis Type 1 with Novel Nonsense Mutations in the ATP8B1 Gene

Case Reports in Gastroenterology, 2022
Benign recurrent intrahepatic cholestasis (BRIC) is a group of genetically heterogeneous autosomal recessive liver disorders characterized by recurrent episodes of jaundice and pruritus.
Ryoichi Miura, Tomokazu Kawaoka, Michio Imamura, Masanari Kosaka, Yusuke Johira, Yuki Shirane, Serami Murakami, Shigeki Yano, Kei Amioka, Kensuke Naruto, Yuwa Ando, Yumi Kosaka, Kenichiro Kodama, Shinsuke Uchikawa, Hatsue Fujino, Atsushi Ono, Takashi Nakahara, Eisuke Murakami, Masami Yamauchi, Takao Hinoi, Hiroshi Aikata   +20 more
doaj   +1 more source

Benign Recurrent Intrahepatic Cholestasis (BRIC): An African Case Report

Case Reports in Gastrointestinal Medicine, 2020
Benign recurrent intrahepatic cholestasis (BRIC) is a rare disorder characterised by recurrent episodes of cholestatic jaundice. First described in 1959, BRIC has been reported in patients all over the world including of African descent.
Adil Salyani, Linda Barasa, Allan Rajula, Sayed K. Ali   +3 more
doaj   +1 more source