Results 61 to 70 of about 1,261,740 (256)

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Bridge naming rules

, 2010
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes."Bridge Program Unit R.L. Groff Revised May 2010."Title from

core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

An Experimental Validated Control Strategy of Maglev Vehicle-Bridge Self-Excited Vibration

Applied Sciences, 2017
This study discusses an experimentally validated control strategy of maglev vehicle-bridge vibration, which degrades the stability of the suspension control, deteriorates the ride comfort, and limits the cost of the magnetic levitation system.
Lianchun Wang, Jinhui Li, Danfeng Zhou, Jie Li   +3 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Prevalence of Respiratory Syncytial Virus in Adult Patients with Respiratory Illnesses in Low to Middle-Income Countries: A Systematic Review and Meta-Analyses

Infectious Diseases and Therapy
Introduction There is a gap in the understanding of the burden of respiratory syncytial virus (RSV) among adults in low, lower-middle, and upper-middle income countries, particularly with regard to up-to-date epidemiological data.
Digant Gupta, Amandeep Kaur, Vikas Verma, Désirée A. M. Van Oorschot, Yolanda Penders, Adriana Guzman-Holst   +5 more
doaj   +1 more source

An overview of performance-based seismic design methodology for bridges

Tạp chí Khoa học và Công nghệ
The Performance-Based Seismic Design (PBSD) is an advanced approach to designing earthquake-resistant structures, ensuring that a building meets specific performance objectives under seismic impacts.
Nguyen Hoang Vinh, Doan Cong Chanh, Phan Hoang Nam, Hoang Phuong Hoa, Gianluca Quinci   +4 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Evaluation of Viability and Adhesion of Human Gingival Fibroblast and the Adhesion of Oral Microflora on Thermally Aged Zirconia and BioHPP Abutment Surfaces: An In Vitro Study

International Journal of Dentistry
Conclusion: Surface roughness affects the bioactivity of the cells. Therefore, for the longevity of implants, a smoother surface is preferred. Even though zirconia showed better results in terms of HGF viability and microbial adhesion in comparison to ...
Ishita Singh, Umesh Y. Pai, B. Thilak Shetty, Shobha J. Rodrigues, Sharon Saldanha, M. Mahesh, K. Shama Prasada, Vignesh Kamath, Prashant Bajantri, Sandipan Mukherjee, Ann Sales   +10 more
doaj   +1 more source

A simplified calculation method for symmetrical loading of a single-span composite string steel structure

Engineering Structures and Technologies, 2019
The article presents single-span composite string steel structure. The article discusses the calculation method for the single-span composite string structure when the load is symmetrical, while the string and bottom cable act as absolutely flexible ...
Edmundas Beivydas
doaj   +1 more source