Results 61 to 70 of about 1,020,994 (316)

Direct Measurement of Dynamics in Road Bridges Using a Bridge Weigh-In-Motion System

open access: yesThe Baltic Journal of Road and Bridge Engineering, 2013
A method is presented of measuring a bridge’s characteristic allowance for dynamic interaction in the form of Assessment Dynamic Ratio. Using a Bridge Weigh-in-Motion system, measurements were taken at a bridge in Slovenia over 58 days.
Eugene J. OBrien   +3 more
doaj   +1 more source

Monitoring Bridge Dynamic Behaviour Using an Instrumented Two Axle Vehicle

open access: yes, 2012
Bridge & Infrastructure Research in Ireland 2010 (BRI 10), Cork, 2-3 September 2010Highway structures such as bridges are subject to continuous degradation primarily due to ageing, loading and environmental factors.
McGetrick, P.   +3 more
core  

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Court Backlogs: Balancing Efficiency and Justice in Singapore

open access: yesOñati Socio-Legal Series, 2017
Access to justice via public dispute resolution in the courts requires a certain number of judges to handle the volume of disputes, and failure to have a critical mass of judicial officers leads to delays or denial of justice.
Helena Whalen-Bridge
doaj  

Study and Renovation of Historical Masonry Arch Bridge

open access: yesThe Baltic Journal of Road and Bridge Engineering, 2013
The aim of this research was the investigation of the properties of clay brick masonry arch bridge materials with a purpose of finding the best methods for reconstruction and renovation of the structure.
Andris Paeglītis   +3 more
doaj   +1 more source

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

open access: yesMolecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini   +1 more
wiley   +1 more source

Autocontrol como predictor de las agresiones autoinformadas entre pares en estudiantes de primaria y secundaria en Medellín, Colombia

open access: yesRevista de Psicología
El Autocontrol es el constructo más influyente en la conducta antisocial y las agresiones entre pares con conductas antisociales. Se indagó la relación entre las agresiones y el autocontrol en 265 estudiantes en Colombia, mediante una investigación ...
Solbey Morillo Puente   +3 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Bridge safety action plan

open access: yes, 2009
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Title from PDF caption (viewed on April 27, 2016).Mode of ...

core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

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