Results 61 to 70 of about 3,128,710 (296)
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Estimation of Extreme Load Effects on Long-Span Bridges Using Traffic Image Data
The Baltic Journal of Road and Bridge Engineering, 2018 This paper proposes an algorithm for the estimation of extreme intensity of traffic load on long-span bridges. Most Weigh-in-Motion technologies do not operate in congested conditions which are the governing cases for these bridges.
Elena Alexandra Micu +3 more
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Court Backlogs: Balancing Efficiency and Justice in Singapore
Oñati Socio-Legal Series, 2017 Access to justice via public dispute resolution in the courts requires a certain number of judges to handle the volume of disputes, and failure to have a critical mass of judicial officers leads to delays or denial of justice.
Helena Whalen-Bridge
doaj
Direct Measurement of Dynamics in Road Bridges Using a Bridge Weigh-In-Motion System
The Baltic Journal of Road and Bridge Engineering, 2013 A method is presented of measuring a bridge’s characteristic allowance for dynamic interaction in the form of Assessment Dynamic Ratio. Using a Bridge Weigh-in-Motion system, measurements were taken at a bridge in Slovenia over 58 days.
Eugene J. OBrien +3 more
doaj +1 more source
Folia Morphologica, 2020 Myocardial bridging (MB) is an anatomical variant in which an epicardial coronary artery passes under a bridge of myocardium. The most commonly affected vessel is the left anterior descending coronary artery, although other branches such as the marginal branches, diagonal branches and posterior descending right coronary artery may be occasionally ...
M, Tiryakioğlu, M N, Aliyu
openaire +3 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Revista de PsicologíaEl Autocontrol es el constructo más influyente en la conducta antisocial y las agresiones entre pares con conductas antisociales. Se indagó la relación entre las agresiones y el autocontrol en 265 estudiantes en Colombia, mediante una investigación ...
Solbey Morillo Puente +3 more
doaj +1 more source
Study and Renovation of Historical Masonry Arch Bridge
The Baltic Journal of Road and Bridge Engineering, 2013 The aim of this research was the investigation of the properties of clay brick masonry arch bridge materials with a purpose of finding the best methods for reconstruction and renovation of the structure.
Andris Paeglītis +3 more
doaj +1 more source
Non-minimal bridge positions of torus knots are stabilized
, 2010 We show that any non-minimal bridge decomposition of a torus knot is stabilized and that $n$-bridge decompositions of a torus knot are unique for any integer $n$. This implies that a knot in a bridge position is a torus knot if and only if there exists a
Bonahon +7 more
core +1 more source