Results 51 to 60 of about 1,261,740 (256)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Bridge and Dementia Study

open access: yes, 2017
The dataset contains a cross section of over 7000 individuals completing a survey exploring the link between the card game Bridge and quality of life.
McDonnell, Diarmuid   +2 more
core   +1 more source

Court Backlogs: Balancing Efficiency and Justice in Singapore

open access: yesOñati Socio-Legal Series, 2017
Access to justice via public dispute resolution in the courts requires a certain number of judges to handle the volume of disputes, and failure to have a critical mass of judicial officers leads to delays or denial of justice.
Helena Whalen-Bridge
doaj  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Autocontrol como predictor de las agresiones autoinformadas entre pares en estudiantes de primaria y secundaria en Medellín, Colombia

open access: yesRevista de Psicología
El Autocontrol es el constructo más influyente en la conducta antisocial y las agresiones entre pares con conductas antisociales. Se indagó la relación entre las agresiones y el autocontrol en 265 estudiantes en Colombia, mediante una investigación ...
Solbey Morillo Puente   +3 more
doaj   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Bridge safety action plan

open access: yes, 2009
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Title from PDF caption (viewed on April 27, 2016).Mode of ...

core  

Evaluation of High-Speed Railway Bridges Based on a Nondestructive Monitoring System

open access: yesApplied Sciences, 2016
Recently, trains’ velocities in Korea increased more than the speed used in the design of some bridges. Accordingly, this paper demonstrates the evaluation of a railway bridge due to high-speed trains’ movement. A nondestructive monitoring system is used
Mosbeh R. Kaloop   +2 more
doaj   +1 more source

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