Results 91 to 100 of about 60,072 (305)

Two – Dimensional Mathematical Model to Study Erosion Problem of Tigris River Banks at Nu’maniyah

Journal of Engineering, 2017
The high and low water levels in Tigris River threaten the banks of the river. The study area is located on the main stream of Tigris River at Nu’maniyah City and the length of the considered reach is 5.4 km, especially the region from 400 m upstream Nu ...
Hayder AbdulAmeer. K. AL-Thamiry, Ass. Prof. Dr., Taymaa Maziad AbdulAzeez, Lecturer   +1 more
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Allosteric Inhibition of Polycomb Repressive Complex 2 by an EZH2‐Selective Small Molecule Inhibitor

Advanced Science, EarlyView.
The study characterizes C36, a highly selective EZH2/PRC2 inhibitor that acts via a novel allosteric mechanism. Unlike previous inhibitors, C36 inhibits EZH2/PRC2 by disrupting the allosteric communication between EZH2 and EED in a SAM‐noncompetitive manner.
Ting Cao, Dongdong Liu, Haishan Gao, Chenyang Qin, Wen Zhang, Ziyun Lu, Dongxia Tan, Yuxiu Qu, Yusong Liu, Zhiran Zou, Hongtao Yu, Wei Qi   +11 more
wiley   +1 more source

ISO20022 Banking Bridge

Abstract This white paper describes an integration module (“Banking Bridge”) that converts ledger-side events from main Ledger (LSL)—including events produced by an AI/reinforcement-learning (RL) minting policy—into ISO 20022 MX payment messages, with an emphasis on pacs.008 (FIToFICustomerCreditTransfer).
openaire   +3 more sources

Bridging the Gap: The Impact of Open Banking on Traditional Banking and FinTech Collaboration

FinTech and AI in Finance
Open banking is revolutionizing the retail banking industry by allowing customers to share their data with third parties. This facilitates the entry of new companies into the market, promoting increased competition, innovation, and improvements in processes such as customer registration and fraud management.
openaire   +2 more sources

Experimental Study of the Effect of Displacement of Vanes Submerged at Channel Width on Distribution of Velocity and Shear Stress in a 180 Degree Bend

Journal of Applied Fluid Mechanics, 2019
Shear stress is a parameter of high significance. Through knowledge of this parameter, assessment of scour or sedimentations at different points of bed is made viable.
Ch. Abdi Chooplou, M. Vaghefi
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Conformational Snapshots of CydDC in a Native Lipid Bilayer Coupling Heme Transport to Antibiotic Resistance

Advanced Science, EarlyView.
Phylogenetic and biochemical analyses of the heme transporter CydDC reveal its functional conservation throughout bacterial evolution and demonstrate its unique asymmetric allosteric mechanism. Furthermore, impairment of CydDC function directly affects bacterial antibiotic resistance and likely compromises antibiotic efficacy through drug efflux.
Lili Yang, Changbin Zhang, Mengyuan Lyu, Yongbo Luo, Jierou Zhang, Yujiao Chen, Lintao Luo, Wen Qiao, Xiangyangpeng Li, Yu Zhou, Zhongling Wei, Yuling Xiao, Qian Niu, Juan Zhou, Guanglin He, Binwu Ying, Zhaoming Su, Hao Chen, Xiaodi Tang, Haohao Dong   +19 more
wiley   +1 more source

A Phase‐Resolved Geometric Deep Learning Framework Maps Structural Determinants of Disease‐Associated Protein Aggregation and Guides Suppressor Design

Advanced Science, EarlyView.
SKALE 2.0 maps disease‐associated protein aggregation as a phase‐resolved structural process, linking mutation‐induced geometric perturbations to nucleation, elongation, and suppressor design. Across neurodegenerative proteins, the framework reveals cryptic aggregation vulnerabilities, separates phase‐concordant and phase‐switching mutations, and ...
Jia Shen Sio, Wei Xuan Wilson Loo, Yan Shan Loo, Wen Xin Tan, Hui Xuan Lim, Huitao Liu, Chen Seng Ng   +6 more
wiley   +1 more source

CHCHD10 Mitigates Alzheimer's Disease‐Related Phenotypes in Association With Epigenetic Remodeling in Directly Reprogrammed Neurons

Advanced Science, EarlyView.
CHCHD10 loss in Alzheimer's disease is associated with mitochondrial dysfunction, epigenomic disruption, and tau pathology. Restoration of CHCHD10 shifts DNA methylation toward a non‐disease state and reduces tau and amyloid pathology, with KATNAL2 acting as a downstream effector.
Teresa M. Thomas, Ching‐Yao Yang, Kexin Zhang, Liam Wetzel, Dina Bugybayeva, Julia Ferguson, Md Mahmudul Hasan, William Samsa, Nandita Patil, Anshul Dash, Tarini Gowda, Xiongwei Zhu, Feixiong Cheng, Tian Liu   +13 more
wiley   +1 more source

An Illustrated Guide for Monitoring and Protecting Bridge Waterways Against Scour - Project TR-515 - Final Report, March 2006 [PDF]

, 2006
This report is a well illustrated and practical Guide intended to aid engineers and engineering technicians in monitoring, maintaining, and protecting bridge waterways so as to mitigate or prevent scour from adversely affecting the structural ...

core  

Pencegahan Gerusan Tebing Pada Jembatan Di Sungai Luk Ulo, Kebumen Jawa Tengah

Jurnal Teknik Hidraulik, 2015
This research was conducted to elaborate the possibility of damages and alternative problem anticipation to protect the new bridge design at Luk Ulo River.
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